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银屑病中的脉络膜厚度。

Choroidal thickness in psoriasis.

作者信息

Kılıç Raşit, Kurt Ali, Acer Ersoy, Öktem Çağlar, Kocamış Özkan

机构信息

Department of Ophthalmology, Faculty of Medicine, Ahi Evran University, Bağbaşı, Sahir Kurutluoğlu Cad. No:100, 40100, Kırşehir, Turkey.

Department of Dermatology, Ahi Evran University Training and Research Hospital, Kırşehir, Turkey.

出版信息

Int Ophthalmol. 2017 Feb;37(1):173-177. doi: 10.1007/s10792-016-0252-1. Epub 2016 May 11.

Abstract

Our aim was to compare the choroidal thickness in psoriasis patients and age- and gender-matched healthy volunteers. A total of 38 psoriasis cases and 38 age- and gender-matched controls were evaluated. The left eye was evaluated in all subjects. The choroidal thicknesses were measured at the subfovea and horizontally across the fovea at 500-μm intervals using enhanced depth imaging spectral domain optical coherence tomography. The points of measurement were 1500 µm temporal and nasal to the fovea. Choroidal thicknesses in psoriasis patients were thicker than those in the controls, but these differences were not statistically significant (P > 0.05). A positive correlation was present between the duration of disease and choroidal thickness at certain measurement points, but there was no significant correlation between the Psoriasis Area and Severity Index score and choroidal thickness. There was no significant difference between psoriasis patients and healthy controls in terms of choroidal thickness. However, choroidal thickness was associated with disease duration.

摘要

我们的目的是比较银屑病患者与年龄和性别匹配的健康志愿者的脉络膜厚度。共评估了38例银屑病患者和38例年龄及性别匹配的对照者。所有受试者均评估左眼。使用增强深度成像光谱域光学相干断层扫描,在黄斑中心凹下以及以500μm间隔水平穿过黄斑中心凹测量脉络膜厚度。测量点位于黄斑中心凹颞侧和鼻侧1500μm处。银屑病患者的脉络膜厚度比对照组厚,但这些差异无统计学意义(P>0.05)。在某些测量点,病程与脉络膜厚度呈正相关,但银屑病面积和严重程度指数评分与脉络膜厚度之间无显著相关性。银屑病患者与健康对照者在脉络膜厚度方面无显著差异。然而,脉络膜厚度与病程相关。

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