Kola Mehmet, Kalkisim Ahmet, Karkucak Murat, Turk Adem, Capkin Erhan, Can Ipek, Serdar Omer Faruk, Mollamehmetoglu Suleyman, Ayar Ahmet
Department of Ophthalmology, Faculty of Medicine, Karadeniz Technical University , Trabzon , Turkey .
Ocul Immunol Inflamm. 2014 Dec;22(6):434-8. doi: 10.3109/09273948.2014.928734. Epub 2014 Jul 2.
Abstract Purpose: To investigate posterior segment (PS) findings in the eye in patients with ankylosing spondylitis (AS).
Eighty-four patients with AS and 63 healthy controls were enrolled. PS evaluations were performed using optical coherence tomography (OCT). Foveal thickness, peripapillary retinal nerve fiber layer thickness, macular volume, ganglion cell complex, and choroidal thickness (CT) values were compared between the groups.
Mean CT was higher in patients with AS (326.5 ± 71.5 µm) than in the healthy controls (286.2 ± 59.5 µm) (p = 0.001). There was no significant difference between patients with AS and the healthy control group in terms of other OCT parameters. There was also no significant correlation between CT, AS activity index, and disease duration.
This is the first study to evaluate effects of AS on CT. CT was high in patients with AS compared to healthy controls.
摘要目的：研究强直性脊柱炎（AS）患者眼部后段（PS）的表现。
纳入84例AS患者和63例健康对照者。使用光学相干断层扫描（OCT）进行PS评估。比较两组之间的黄斑中心凹厚度、视乳头周围视网膜神经纤维层厚度、黄斑体积、神经节细胞复合体和脉络膜厚度（CT）值。
AS患者的平均CT（326.5±71.5μm）高于健康对照者（286.2±59.5μm）（p = 0.001）。在其他OCT参数方面，AS患者与健康对照组之间无显著差异。CT、AS活动指数和病程之间也无显著相关性。
这是第一项评估AS对CT影响的研究。与健康对照者相比，AS患者的CT较高。
