Suppr超能文献

CHADS-VASc评分可预测接受直接经皮冠状动脉介入治疗的ST段抬高型心肌梗死患者的院内及长期临床结局。

CHADS-VASc Score Predicts In-Hospital and Long-Term Clinical Outcomes in Patients With ST-Segment Elevation Myocardial Infarction Who Were Undergoing Primary Percutaneous Coronary Intervention.

作者信息

Bozbay Mehmet, Uyarel Huseyin, Cicek Gokhan, Oz Ahmet, Keskin Muhammed, Murat Ahmet, Yildirim Ersin, Karaca Gurkan, Ergelen Mehmet, Eren Mehmet

机构信息

1 Department of Cardiology, Dr Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey.

2 Department of Cardiology, School of Medicine, Bezmi Alem Vakif University, Istanbul, Turkey.

出版信息

Clin Appl Thromb Hemost. 2017 Mar;23(2):132-138. doi: 10.1177/1076029616646874. Epub 2016 Jul 9.

Abstract

CHADS-VASc score includes similar risk factors for coronary artery disease. We hypothesized that admission CHADS-VASc score might be predictive of adverse clinical outcomes for patients with ST-segment elevation myocardial infarction (STEMI) who were undergoing primary percutaneous coronary intervention. A total of 647 patients with STEMI enrolled in this study. The study population was divided into 2 groups according to their admission CHADS-VASc score. The low group (n = 521) was defined as CHADS-VASc score ≤2, and the high group (n = 126) was defined as CHADS-VASc score >2. Patients in the high group had significantly higher incidence of in-hospital cardiovascular mortality (8.7% vs 1.9%; P < .001). Long-term mortality was significantly frequent in the high group (13.4% vs 3.6%, P < .001). Hypertension, admission CHADS-VASc score, and Killip class >1 were independent predictors of long-term mortality. Admission CHA2DS2-VASc score >2 was identified as an effective cutoff point for long-term mortality (area under curve = 0.821; 95% confidence interval: 0.76-0.89; P < .001). CHADS-VASc score is a simple, very useful, easily remembered bedside score for predicting in-hospital and long-term adverse clinical outcomes in STEMI.

摘要

CHADS-VASc评分包含与冠状动脉疾病相似的危险因素。我们推测,入院时的CHADS-VASc评分可能对接受直接经皮冠状动脉介入治疗的ST段抬高型心肌梗死(STEMI)患者的不良临床结局具有预测作用。本研究共纳入647例STEMI患者。根据入院时的CHADS-VASc评分将研究人群分为两组。低分组(n = 521)定义为CHADS-VASc评分≤2,高分组(n = 126)定义为CHADS-VASc评分>2。高分组患者的院内心血管死亡率显著更高(8.7% 对1.9%;P < .001)。高分组的长期死亡率明显更高(13.4% 对3.6%,P < .001)。高血压、入院时的CHADS-VASc评分以及Killip分级>1是长期死亡率的独立预测因素。入院时的CHA2DS2-VASc评分>2被确定为长期死亡率的有效截断点(曲线下面积 = 0.821;95% 置信区间:0.76 - 0.89;P < .001)。CHADS-VASc评分是一种简单、非常有用且易于记忆的床旁评分,可用于预测STEMI患者的院内及长期不良临床结局。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验