再梗死相关危险因素评估：一项多中心观察性研究。
Evaluation of Risk Factors Associated with Reinfarction: A Multicenter Observational Study.
作者信息
Mal Kheraj, Awan Inayatullah D, Shaukat Faizan
机构信息
Cardiology, National Institute of Cardiovascular System, Sukkur, PAK.
Psychiatry, Ghulam Muhammad Mahar Medical College, Sukkur, PAK.
出版信息
Cureus. 2019 Nov 3;11(11):e6063. doi: 10.7759/cureus.6063.
Abstract
INTRODUCTION
Reinfarction after incidence of myocardial infarction is a serious complication and is responsible for high mortality. Various factors are responsible for reinfarction including smoking, prior procedures or surgeries, and use of medications such as aspirin, β-blocker, and angiotensin-converting enzyme Iihibitor or angiotensin receptor blockers.
MATERIAL AND METHODS
This prospective study was conducted with 243 participants. Participants were divided into two groups: patients who had a reinfarction during hospital and patients who did not.
RESULTS
There were 142 (58.4%) men and 101 (41.6%) women in the study. A total of 17 (6.9%) patients had reinfarction. Age (68.4±10.9 vs. 64.4±11.8; 0.001), diabetes (47.05% vs. 22.12%; 0.02), and history of myocardial infarction (29.5% vs. 11.4%; 0.02) were identified as risk factors for reinfarction Conclusion: Our study reports that certain parameters such as age, obesity, diabetes mellitus,, and history of myocardial infarction can be used to assess the risk of reinfarction among these patients.
摘要
引言
心肌梗死后再梗死是一种严重的并发症，死亡率很高。多种因素可导致再梗死，包括吸烟、既往的操作或手术，以及使用阿司匹林、β受体阻滞剂、血管紧张素转换酶抑制剂或血管紧张素受体阻滞剂等药物。
材料与方法
本前瞻性研究纳入了243名参与者。参与者被分为两组：住院期间发生再梗死的患者和未发生再梗死的患者。
结果
研究中有142名（58.4%）男性和101名（41.6%）女性。共有17名（6.9%）患者发生再梗死。年龄（68.4±10.9对64.4±11.8；P=0.001）、糖尿病（47.05%对22.12%；P=0.02）和心肌梗死病史（29.5%对11.4%；P=0.02）被确定为再梗死的危险因素。结论：我们的研究报告称，年龄、肥胖、糖尿病和心肌梗死病史等特定参数可用于评估这些患者发生再梗死的风险。
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3
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