奎宁与长QT综合征的基本知识：一位患者患关节炎、（酒精性）饮料和抽筋的不幸遭遇。
Quinine and the ABCs of Long QT: A Patient's Misfortune with Arthritis, (Alcoholic) Beverages, and Cramps.
作者信息
Sheehan Elyce T, Frizzell Jarrod D, Gabaldon Jude, West Michael B
机构信息
Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA.
San Juan Regional Medical Center, Farmington, NM, USA.
出版信息
J Gen Intern Med. 2016 Oct;31(10):1254-7. doi: 10.1007/s11606-016-3738-7. Epub 2016 May 12.
A 91-year-old woman presented to the emergency department by ambulance after her family found her minimally responsive. Telemetry monitoring demonstrated episodes of non-sustained polymorphic ventricular tachycardia (PMVT) associated with significantly prolonged repolarization. Her medical history revealed that she was taking quinine or a derivative in three different forms: hydroxychloroquine, quinine sulfate (for leg cramps), and her gin mixed with tonic water (containing quinine). The present case is illustrative of classic etiologies and findings of acquired long QT syndrome, and serves as an important reminder for providers to take a complete medication history, including use of duplicative and alternative medicines and type of alcohol consumption.
一名91岁女性在家人发现她反应极其迟钝后，由救护车送往急诊科。遥测监测显示有非持续性多形性室性心动过速（PMVT）发作，伴有明显延长的复极化。她的病史显示，她正在服用三种不同形式的奎宁或其衍生物：羟氯喹、硫酸奎宁（用于治疗腿部痉挛），以及她喝的杜松子酒加奎宁水（含奎宁）。本病例说明了获得性长QT综合征的典型病因和表现，并提醒医疗人员要全面了解用药史，包括重复用药、替代药物的使用情况以及饮酒类型。
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