Cazzola G A, Valletta E A, Mastella G
Servizio Pediatrico Speciale, Ospedale Civile Maggiore - Verona, Italia.
Pediatr Med Chir. 1989 Jan-Feb;11(1):73-5.
Five patients with recurrent infections of the lower respiratory tract, chronic bronchial suppuration and significant defect of polymorphonuclear granulocyte (PMN) motility were studied. Clinical evaluation and in vitro studies of PMN motility were performed before, during and after the treatment with levamisole chlorhydrate (2.5 mg/Kg twice a week). Clinical improvement was obtained in all the patients, together with a significant increase in the chemotactic response of PMN. No side effects were reported. After a follow-up of 7-18 months PMN chemotaxis remained normal in all the patients and a reappearance of respiratory symptoms was observed only in one subject.
对5例下呼吸道反复感染、慢性支气管化脓且多形核粒细胞（PMN）运动功能显著缺陷的患者进行了研究。在用盐酸左旋咪唑（2.5mg/kg，每周两次）治疗前、治疗期间及治疗后，均进行了临床评估和PMN运动功能的体外研究。所有患者均获得临床改善，同时PMN趋化反应显著增加。未报告有副作用。经过7至18个月的随访，所有患者的PMN趋化性均保持正常，仅1例患者出现呼吸道症状复发。
