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站立位马匹腰骶部硬膜外腔镜检查的可行性与安全性

Feasibility and safety of lumbosacral epiduroscopy in the standing horse.

作者信息

Shrauner B, Blikslager A, Davis J, Campbell N, Law M, Lustgarten M, Prange T

机构信息

College of Veterinary Medicine, North Carolina State University, Raleigh, USA.

出版信息

Equine Vet J. 2017 May;49(3):322-328. doi: 10.1111/evj.12591. Epub 2016 Jul 4.

Abstract

REASONS FOR PERFORMING STUDY

The large size of the adult horse prevents the use of advanced imaging modalities in most areas of the axial skeleton, including the lumbosacral vertebral column. Traditional imaging techniques are frequently unable to pinpoint the underlying pathology in horses with caudal back pain. In man, lumbosacral epiduroscopy is used to diagnose and treat subjects with chronic back and leg pain. This technique may close the diagnostic gap in horses with similar clinical signs.

OBJECTIVES

To evaluate the safety and feasibility of lumbosacral epiduroscopy in the standing adult horse.

STUDY DESIGN

Descriptive, experimental study.

METHODS

Seven adult horses weighing 504-578 kg were sedated and restrained in stocks in preparation for aseptic surgery. Vascular dilators of increasing size were inserted cranial to the first moveable vertebra caudal to the sacrum to facilitate a minimally invasive approach into the epidural space. A flexible video-endoscope was introduced and advanced as far as its 60-cm working length permitted. Pre-, intra- and post-operative plasma cortisol samples were collected, and neurological and lameness examinations were performed prior to and during the 2 weeks following the procedure. Post-mortem examinations were conducted in 5 of the 7 horses.

RESULTS

Standing lumbosacral epiduroscopy was well tolerated by all horses. The anatomic structures in the epidural space (dura mater, spinal nerve roots, fat and blood vessels) were followed as far cranial as the thoracolumbar region. No complications related to the procedure were noted in the 2-week monitoring period following epiduroscopy. Small, organised haematomas were identified in the sacral epidural space during necropsy in one horse. No abnormalities were seen in the other 4 animals.

CONCLUSIONS

Lumbosacral epiduroscopy can be performed safely in sedated standing horses. The procedure may become a valuable diagnostic tool in horses with caudal back or hindlimb pain of unknown origin.

摘要

开展本研究的原因

成年马体型较大,这使得在包括腰骶部脊柱在内的大部分中轴骨骼区域无法使用先进的成像方式。传统成像技术常常无法精准确定患有尾部疼痛的马匹的潜在病变。在人类中,腰骶部硬膜外腔镜检查用于诊断和治疗患有慢性腰腿痛的患者。该技术可能会填补具有类似临床症状的马匹的诊断空白。

目的

评估成年站立马进行腰骶部硬膜外腔镜检查的安全性和可行性。

研究设计

描述性实验研究。

方法

对7匹体重在504 - 578千克的成年马进行镇静并固定在畜栏中,为无菌手术做准备。将尺寸逐渐增大的血管扩张器插入到骶骨尾侧第一个可活动椎骨的头侧,以利于采用微创方法进入硬膜外腔。引入一根柔性视频内窥镜,并在其60厘米工作长度允许的范围内推进。采集术前、术中和术后的血浆皮质醇样本,并在手术前及术后2周内进行神经学和跛行检查。对7匹马中的5匹进行了尸体剖检。

结果

所有马匹对站立位腰骶部硬膜外腔镜检查耐受性良好。硬膜外腔的解剖结构(硬脊膜、脊神经根、脂肪和血管)一直追踪到头侧的胸腰段区域。硬膜外腔镜检查后的2周监测期内未发现与该操作相关的并发症。在一匹马的尸体剖检中,在骶部硬膜外腔发现了小的、有组织的血肿。其他4只动物未发现异常。

结论

在镇静的站立马中可以安全地进行腰骶部硬膜外腔镜检查。该操作可能成为患有不明原因尾部或后肢疼痛的马匹的一种有价值的诊断工具。

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