Chevrolet J C
Division de pneumologie, Soins intensifs médicaux, Hôpital cantonal universitaire, Genève.
Schweiz Med Wochenschr. 1989 Mar 18;119(11):335-40.
Although arterial blood gas analysis remains the "gold standard" for oxygen (O2) and carbon dioxide (CO2) measurements during critical illness, several new techniques are now available for clinicians in this field, i.e. pulse oximetry, transcutaneous (PtcO2) and transconjunctival (PcjO2) O2 monitoring, CO2 continuous measurements in expired gases (capnography) and transcutaneous PCO2 (PtcCO2). While it seems too early to assign a definite role to all these techniques in the management of critically ill patients, several points can be emphasized: 1. pulse oximetry is a cheap, versatile device for monitoring of nonhypoxemic patients; 2. PtcO2 is a good index of poor skin oxygenation and is related to PaO2, but this index should be interpreted with caution in unsteady patients; perhaps its main value is as an early warning that "something is wrong with the patient". PcjO2 may be promising, but more data are needed; 3. PtcCO2 and capnography seem more suitable for research purposes or for patient monitoring in the operating theatre. Finally, it should be emphasized that invasive arterial blood gas measurements using an indwelliing arterial catheter are safe and provide with the best possible acid-base and hemodynamic monitoring. Noncontinuous monitoring of blood gases and, perhaps, the delay between arterial puncture and completion of the analysis seem to be the only drawbacks of this technique.
尽管动脉血气分析仍是危重病期间氧(O₂)和二氧化碳(CO₂)测量的“金标准”,但该领域的临床医生现在有几种新技术可供使用,即脉搏血氧饱和度测定法、经皮(PtcO₂)和经结膜(PcjO₂)氧监测、呼出气体中二氧化碳的连续测量(二氧化碳图)和经皮PCO₂(PtcCO₂)。虽然现在就确定所有这些技术在危重病患者管理中的明确作用似乎为时过早,但可以强调几点:1. 脉搏血氧饱和度测定法是一种用于监测非低氧血症患者的廉价、多功能设备;2. PtcO₂是皮肤氧合不良的良好指标,与PaO₂相关,但在病情不稳定的患者中应谨慎解释该指标;也许它的主要价值是作为“患者出现问题”的早期预警。PcjO₂可能很有前景,但需要更多数据;3. PtcCO₂和二氧化碳图似乎更适合研究目的或手术室中的患者监测。最后,应该强调的是,使用留置动脉导管进行有创动脉血气测量是安全的,并能提供最佳的酸碱和血流动力学监测。血气的非连续监测以及动脉穿刺与分析完成之间的延迟似乎是该技术的唯一缺点。