Lieve Krystien V, van der Werf Christian, Wilde Arthur A
Heart Centre, Department of Clinical and Experimental Cardiology, Academic Medical Centre.
Circ J. 2016 May 25;80(6):1285-91. doi: 10.1253/circj.CJ-16-0326. Epub 2016 May 13.
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited cardiac arrhythmia disorder that is characterized by emotion- and exercise-induced polymorphic ventricular arrhythmias and may lead to sudden cardiac death (SCD). CPVT plays an important role in SCD in the young and therefore recognition and adequate treatment of the disease are of vital importance. In the past years tremendous improvements have been made in the diagnostic methods and treatment of the disease. In this review, we summarize the clinical characteristics, genetics, and diagnostic and therapeutic strategies of CPVT and describe the most recent advances and some of the current challenges. (Circ J 2016; 80: 1285-1291).
儿茶酚胺能多形性室性心动过速（CPVT）是一种遗传性心律失常疾病，其特征为情绪和运动诱发的多形性室性心律失常，并可能导致心源性猝死（SCD）。CPVT在年轻人的心源性猝死中起重要作用，因此对该疾病的识别和适当治疗至关重要。在过去几年中，该疾病的诊断方法和治疗取得了巨大进展。在本综述中，我们总结了CPVT的临床特征、遗传学以及诊断和治疗策略，并描述了最新进展和当前的一些挑战。（《循环杂志》2016年；80: 1285 - 1291）
