Pohl Veronika, Schuh Christian, Fischer Michael B, Haas Robert
Int J Oral Maxillofac Implants. 2016 May-Jun;31(3):622-30. doi: 10.11607/jomi.4172.
This prospective longitudinal study reports on the results in patients given autologous tooth material for augmentation in a sinus elevation procedure.
Six patients with inadequate bone supply for augmentation in the maxillary posterior tooth region and at least one impacted maxillary third molar underwent sinus elevation surgery with lateral access using the particulate tooth material. One of the patients received four implants during the same session, while the other patients had a total of 15 implants placed after a healing phase of an average 5.5 months. Drill cylinders collected from the implant bed during the procedure were subjected to histologic/immunohistochemical evaluation.
All six patients showed normal and unobtrusive postoperative healing, having undergone prosthetic restoration up to 5 years before. The average peri-implant probing pocket depth after a period of up to 5 years ranged between 1.86 mm (mesial and lingual) and 2.07 mm (distal and buccal). No bleeding could be triggered with any of the peri-implant probes. The average peri-implant bone resorption measured during the first year was up to 0.63 mm, with the lowest being 0 mm and the maximum 2.9 mm. Peri-implant bone remained stable for the follow-up time of up to 5 years. Histologically, six biopsy specimens collected from five patients showed osteoconductive osteogenesis with encapsulation of tooth enamel and dentin portions and partial resorption of the tooth components. Cementum shares were no longer discernible. Immunohistochemical assessment showed intense new vessel formation that could be observed in the area of loose stroma of reorganized tissue in the augmented area.
Within the limits of these preliminary results and with adequate consideration of the small number of patients included, the use of autogenous crushed tooth material from impacted third molars may represent an alternative augmentation material for use in sinus elevation procedures.
本前瞻性纵向研究报告了在鼻窦提升手术中使用自体牙材料进行增量治疗的患者的结果。
6例上颌后牙区骨量不足需增量且至少有一颗上颌阻生第三磨牙的患者,采用颗粒状牙材料经外侧入路进行鼻窦提升手术。其中1例患者在同一次手术中植入4枚种植体,其他患者在平均5.5个月的愈合期后共植入15枚种植体。手术过程中从种植床采集的钻取圆柱体进行组织学/免疫组织化学评估。
所有6例患者术后愈合正常且无明显异常,术前已进行了长达5年的修复治疗。在长达5年的观察期内,种植体周围平均探诊深度在1.86mm(近中和舌侧)至2.07mm(远中和颊侧)之间。种植体周围探针均未引发出血。第一年测量的种植体周围平均骨吸收量高达0.63mm,最低为0mm,最高为2.9mm。在长达5年的随访期内,种植体周围骨保持稳定。组织学上,从5例患者采集的6份活检标本显示为骨传导性成骨,牙釉质和牙本质部分被包裹,牙齿成分部分吸收。牙骨质部分已无法辨认。免疫组织化学评估显示,在增量区域重组组织的疏松基质区域可观察到强烈的新血管形成。
在这些初步结果的范围内,并充分考虑到纳入患者数量较少的情况,使用来自阻生第三磨牙的自体碎牙材料可能是鼻窦提升手术中一种可供选择的增量材料。