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自体牙组织移植用于牙槽骨重建的研究:一项系统评价

The Use of Autogenous Teeth Tissues Grafts for Alveolar Bone Reconstruction: a Systematic Review.

作者信息

Peceliunaite Gabriele, Pliavga Vykintas, Juodzbalys Gintaras

机构信息

Department of Maxillofacial Surgery, Faculty of Odontology, Medical Academy, Lithuanian University of Health Sciences, KaunasLithuania.

出版信息

J Oral Maxillofac Res. 2023 Dec 31;14(4):e2. doi: 10.5037/jomr.2023.14402. eCollection 2023 Oct-Dec.

Abstract

OBJECTIVES

Enough bone around the implant is an important factor in ensuring the stability and longevity of the implant. Therefore, alveolar bone regeneration procedures are often required. A relatively new bone substitute is made from autogenous teeth. There are more and more studies in the scientific literature that perform regenerative alveolar bone procedures using autogenous tissues substitutes made from extracted teeth. The objective of this systematic literature review is to systematize information and present conclusions about the effectiveness of this regenerative material.

MATERIAL AND METHODS

Scientific articles were selected using the PRISMA recommendations. Publications have been carried out since January 1, 2012 to January 1, 2022. The review includes articles in English, clinical studies in humans who underwent bone augmentation prior to or during dental implantation using an autogenous teeth tissues substitute.

RESULTS

A total of 7 publications were included in this systematic literature review. Summarizing the data of the publications, 258 patients participated in the studies, 240 subjects were included in the results for various reasons, and a total of 298 implants were inserted. No statistically significant results were found in the five studies. Two studies comparing autogenous tooth graft with xenogeneic bone graft and autogenous teeth tissues showed statistically significant positive results in autogenous tooth group.

CONCLUSIONS

Within the limitations of this study, autogenous tissues graft derived from teeth are an effective material and can be used as an alternative to other bone grafts existing on the market. Further studies with a longer follow-up period are needed to validate these findings.

摘要

目的

种植体周围有足够的骨组织是确保种植体稳定性和长期使用的重要因素。因此,通常需要进行牙槽骨再生手术。一种相对较新的骨替代物是由自体牙制成的。科学文献中越来越多的研究使用从拔除牙齿制成的自体组织替代物进行牙槽骨再生手术。本系统文献综述的目的是整理信息并就这种再生材料的有效性得出结论。

材料与方法

使用PRISMA推荐方法选择科学文章。发表时间为2012年1月1日至2022年1月1日。该综述包括英文文章,以及关于在牙种植术前或术中使用自体牙组织替代物进行骨增量的人体临床研究。

结果

本系统文献综述共纳入7篇出版物。总结这些出版物的数据,258名患者参与了研究,240名受试者因各种原因被纳入结果分析,共植入298颗种植体。五项研究未发现具有统计学意义的结果。两项比较自体牙移植与异种骨移植及自体牙组织的研究显示,自体牙组有统计学意义的阳性结果。

结论

在本研究的局限性范围内,源自牙齿的自体组织移植是一种有效的材料,可作为市场上现有其他骨移植材料的替代品。需要进行更长随访期的进一步研究来验证这些发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bef/10783878/a6758ff8072f/jomr-14-e2-g001.jpg

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