近红外上转换化学传感器用于威尔逊病中 Cu(2+) 的体内检测。
Near-Infrared Upconversion Chemodosimeter for In Vivo Detection of Cu(2+) in Wilson Disease.
机构信息
Department of Chemistry and State Key Laboratory of Molecular Engineering of Polymers Institute of Biomedicine Sciences and Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University, Shanghai, 200433, P. R. China.
Department of Neurology, Huashan Hospital, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, 200040, P. R. China.
出版信息
Adv Mater. 2016 Aug;28(31):6625-30. doi: 10.1002/adma.201601140. Epub 2016 May 17.
Near-infrared upconversion chemodosimetry is a promising detection method by virtue of the frequency upconversion technique, which shows very high sensitivity and selectivity for the detection of Cu(2+) ions in vitro and in vivo. This method offers a new opportunity for noninvasive diagnosis of Wilson disease associated with Cu(2+) detection in clinical medicine.
近红外上转换化学计量学是一种很有前途的检测方法，它利用了频率上转换技术，对体外和体内 Cu(2+)离子的检测具有非常高的灵敏度和选择性。该方法为临床中与 Cu(2+)检测相关的威尔逊病的无创诊断提供了新的机会。
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