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(18)F-FDG PET/CT 表现酷似恶性淋巴瘤的急性 EBV 感染

(18)F-FDG PET/CT Findings in Acute Epstein-Barr Virus Infection Mimicking Malignant Lymphoma.

机构信息

Department of Infectious Diseases, Copenhagen University Hospital Hvidovre, Kettegaards Allé 30, DK-2650 Hvidovre, Denmark.

Department of Clinical Physiology & Nuclear Medicine, Copenhagen University Hospital, DK-2650 Hvidovre, Denmark.

出版信息

Diagnostics (Basel). 2016 May 12;6(2):18. doi: 10.3390/diagnostics6020018.

DOI:10.3390/diagnostics6020018
PMID:27187482
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4931413/
Abstract

We present a case demonstrating the diagnostic work-up and follow-up of a patient with acute Epstein-Barr virus (EBV) infection in which the clinical picture and imaging on (18)F-FDG PET/CT mimicked malignant lymphoma. Follow-up (18)F-FDG PET/CT scan in the patient performed 7 weeks after the abnormal scan revealed complete resolution of the metabolically active disease in the neck, axillas, lung hili, and spleen. This case highlights inflammation as one of the most well established false positives when interpreting (18)F-FDG PET/CT scans.

摘要

我们呈现了一个病例,展示了一位急性 EBV 感染患者的诊断过程和随访情况,其临床表现和影像学表现(18)F-FDG PET/CT 类似于恶性淋巴瘤。在异常扫描后 7 周对患者进行的(18)F-FDG PET/CT 随访扫描显示颈部、腋窝、肺门和脾脏的代谢活跃性疾病完全消退。本病例强调了炎症是解释(18)F-FDG PET/CT 扫描时最常见的假阳性之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6830/4931413/6c18d716a1d8/diagnostics-06-00018-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6830/4931413/a05f9c77309c/diagnostics-06-00018-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6830/4931413/6c18d716a1d8/diagnostics-06-00018-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6830/4931413/a05f9c77309c/diagnostics-06-00018-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6830/4931413/6c18d716a1d8/diagnostics-06-00018-g002.jpg

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本文引用的文献

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FDG PET/CT findings in acute adult mononucleosis mimicking malignant lymphoma.氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描(FDG PET/CT)在酷似恶性淋巴瘤的成人急性单核细胞增多症中的表现
Eur J Haematol. 2008 Aug;81(2):154-6. doi: 10.1111/j.1600-0609.2008.01088.x. Epub 2008 May 6.
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Lymphadenopathy resulting from acute hepatitis C infection mimicking metastatic breast carcinoma on FDG PET/CT.
模拟淋巴瘤复发的造口部位感染:氟代脱氧葡萄糖正电子发射断层扫描-计算机断层扫描中的潜在陷阱
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Two cases of angioimmunoblastic T-cell lymphoma with concomitant positive serology for acute Epstein-Barr virus infection.两例血管免疫母细胞性T细胞淋巴瘤合并急性爱泼斯坦-巴尔病毒感染血清学阳性。
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