Lifshitz F, Moses N
Department of Pediatrics, North Shore University Hospital, Manhasset, NY 11030.
Am J Dis Child. 1989 May;143(5):537-42.
We describe 8 children among a group of 40 in whom growth failure was associated with unsupervised dietary treatment of hypercholesterolemia. In 3 children, nutritional dwarfing ensued, and in 5, weight loss or insufficient weight gain occurred. Children with growth failure consumed significantly less energy and zinc than those children growing well. The dietary intakes of the 3 children with nutritional dwarfing were the most markedly deficient in total energy, fat, and micronutrients. These data suggest that the diagnosis and dietary treatment of hypercholesterolemia have potentially adverse consequences. Overzealous application of a low-fat, low-cholesterol diet may lead to growth failure due to inadequate intake of energy, vitamins, and minerals. Careful monitoring of children receiving modified fat and cholesterol intakes for hypercholesterolemia treatment is mandatory to ensure adequate nutrition for normal growth and development.
我们描述了40名儿童中有8名儿童，其生长发育迟缓与高胆固醇血症的无监督饮食治疗有关。3名儿童出现了营养性侏儒症，5名儿童体重减轻或体重增加不足。生长发育迟缓的儿童比生长良好的儿童摄入的能量和锌明显更少。3名患有营养性侏儒症的儿童的饮食摄入量在总能量、脂肪和微量营养素方面最为明显不足。这些数据表明，高胆固醇血症的诊断和饮食治疗可能会产生不良后果。过度严格地应用低脂、低胆固醇饮食可能会因能量、维生素和矿物质摄入不足而导致生长发育迟缓。对接受高胆固醇血症治疗且调整了脂肪和胆固醇摄入量的儿童进行仔细监测，对于确保正常生长发育所需的充足营养是必不可少的。
