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儿童播散性组织细胞肉瘤:具有8年生存期的临床病理二分法

Disseminated histiocytic sarcoma in a child: a clinicopathological dichotomy with 8 years survival.

作者信息

Sharma Shilpa, Das Prasenjit, Dinda Amit K, Gupta Devendra K

机构信息

Department of Pediatric Surgery, All India Institute of Medical Sciences, New Delhi, Delhi, India.

Department of Pathology, All India Institute of Medical Sciences, New Delhi, Delhi, India.

出版信息

BMJ Case Rep. 2016 May 17;2016:bcr2015213871. doi: 10.1136/bcr-2015-213871.

Abstract

A 3-year-old girl presented with a non-healing ulcer, originating as a pustule over the right anterior chest wall of 1½ month duration associated with high fever. A subcutaneous nodule along with right apical and anterior axillary lymph nodes was palpable. Abdominal ultrasound and chest skiagram were normal. Fine needle aspiration cytology (FNAC) from the axillary lymph node was suggestive of embryonal rhabdomyosarcoma. Bone marrow aspirate was normal. The ulcer and subcutaneous nodule were excised completely with adequate margins. Histopathological examinations were compatible with malignancy of histiocytic origin with clear resected margins. The axillary nodes were free of tumour. Adjuvant chemotherapy was given for 13 months. The patient is doing well at 8 years follow-up.

摘要

一名3岁女童出现一处不愈合溃疡,最初为右前胸壁的脓疱,持续1个半月,伴有高热。可触及一个皮下结节以及右侧腋窝和腋下淋巴结。腹部超声和胸部X光检查正常。腋窝淋巴结细针穿刺细胞学检查(FNAC)提示胚胎性横纹肌肉瘤。骨髓穿刺正常。溃疡和皮下结节被完整切除,切缘足够。组织病理学检查结果与组织细胞来源的恶性肿瘤相符,切缘清晰。腋窝淋巴结无肿瘤。给予了13个月的辅助化疗。在8年的随访中,患者情况良好。

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