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鼻腔梭形细胞癌——一例报告

Spindle Cell Carcinoma of Nasal Cavity- A Case Report.

作者信息

Mistry Priyank, Mittal Abhishek, Nagpal Tapan

机构信息

PG Resident, Department of ENT, Sumandeep Vidyapeeth , Vadodara, Gujarat, India .

Professor, Department of ENT, Sumandeep Vidyapeeth , Vadodara, Gujarat, India .

出版信息

J Clin Diagn Res. 2016 Apr;10(4):MD01-2. doi: 10.7860/JCDR/2016/17468.7576. Epub 2016 Apr 1.

Abstract

Spindle Cell Carcinoma (SpCC), also known as Sarcomatoid Carcinoma, is a rare and peculiar biphasic malignant neoplasm that occurs mainly in the upper aero-digestive tract, mostly in larynx. SCC accounts for 3% of all squamous cell carcinomas (SCCs) in the head and neck region. It is a rare variant of SCC which shows spindled or pleomorphic tumour cells simulating a true sarcoma. We present a case report of SpCC nasal cavity in a 50-year-old female patient, presented with intermittent epistaxis from left nasal cavity. On physical examination, the patient had an ulcero-exophytic type of mass in the left nasal cavity and a smooth bulge on the left side of anterior hard palate. Patient underwent excision of nasal mass along with partial palatectomy by facial degloving approach and reconstruction of palate with naso-labial flap. The postoperative histopathological report showed SCC. Surgery forms the mainstay of treatment. Radiotherapy and Chemotherapy is warranted in order to improve treatment results. As only few cases have been reported, we report a case of this rare entity to contribute for better understanding and awareness of this rare malignancy.

摘要

梭形细胞癌(SpCC),也称为肉瘤样癌,是一种罕见且特殊的双相恶性肿瘤,主要发生在上呼吸消化道,多见于喉部。梭形细胞癌占头颈部所有鳞状细胞癌(SCC)的3%。它是鳞状细胞癌的一种罕见变体,表现为梭形或多形性肿瘤细胞,类似真正的肉瘤。我们报告一例50岁女性患者的鼻腔梭形细胞癌病例,该患者表现为左侧鼻腔间歇性鼻出血。体格检查时,患者左侧鼻腔有溃疡外生性肿物,前硬腭左侧有光滑隆起。患者通过面部揭翻术切除鼻腔肿物并进行部分腭切除术,并用鼻唇瓣修复腭部。术后组织病理学报告显示为鳞状细胞癌。手术是主要的治疗方法。放疗和化疗有助于提高治疗效果。由于仅报道了少数病例,我们报告此罕见病例,以促进对这种罕见恶性肿瘤的更好理解和认识。

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