Ghosal Rhitam, Roychowdhury Durba, Chatterjee Rudra Prasad, Sultana Mehebuba, Sinha Sangeeta
Oral and Maxillofacial Pathology, Guru Nanak Institute of Dental Sciences and Research, Kolkata, IND.
Cureus. 2024 Feb 4;16(2):e53565. doi: 10.7759/cureus.53565. eCollection 2024 Feb.
Spindle cell carcinoma (SpCC) or sarcomatoid carcinoma is an uncommon biphasic malignant neoplasm occurring mainly in the upper aerodigestive tract. It has spindled or pleomorphic tumor cells simulating a true sarcoma with epithelial origin. WHO recognized this tumor as an aggressive variant of squamous cell carcinoma and further designated it as spindle cell carcinoma. This neoplasm is known for its propensity of recurrence and metastasis reinforcing the importance of its proper diagnosis. In our case report, we talk about sarcomatoid carcinoma involving the oral cavity having a high metastasizing rate according to histopathological and immunohistochemical features.
梭形细胞癌(SpCC)或肉瘤样癌是一种罕见的双相性恶性肿瘤,主要发生在上呼吸消化道。它具有梭形或多形性肿瘤细胞,模拟起源于上皮的真正肉瘤。世界卫生组织将这种肿瘤认定为鳞状细胞癌的侵袭性变体,并进一步将其命名为梭形细胞癌。这种肿瘤以其复发和转移倾向而闻名,这凸显了正确诊断它的重要性。在我们的病例报告中,我们讨论了根据组织病理学和免疫组化特征显示具有高转移率的累及口腔的肉瘤样癌。