新生儿2型单纯疱疹病毒皮肤感染：一例报告

Cutaneous neonatal herpes simplex virus infection type 2: a case report.

作者信息

Bittencourt Maraya de Jesus Semblano, Freitas Lívia Karlla Marinho, Drago Marion Guimarães, Carvalho Alessandra Haber, Nascimento Bianca Angelina Macêdo do

机构信息

Universidade Federal do Pará, Belém, PA, Brazil.

出版信息

An Bras Dermatol. 2016 Apr;91(2):216-8. doi: 10.1590/abd1806-4841.20163870.

DOI:10.1590/abd1806-4841.20163870

PMID:27192523

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4861571/

Abstract

Neonatal herpes is a serious condition. Newborns can be contaminated in utero via transplacental hematogenic transmission, upon delivery (the most frequent route), or during the postnatal period (indirect transmission). Optimal management requires prompt and accurate recognition, particularly in newborns, in order to prevent complications. Acyclovir is the treatment of choice, but its implementation is often delayed while awaiting test results, such as PCR and serology. Cytology for diagnostic purposes is rarely used in dermatology, despite the quick and reliable results. We report a case of neonatal herpes caused by type 2 herpes simplex virus diagnosed by cytology.

摘要

新生儿疱疹是一种严重的病症。新生儿可在子宫内通过胎盘血源性传播、分娩时（最常见的途径）或出生后时期（间接传播）受到感染。最佳治疗需要迅速而准确的诊断，尤其是对新生儿而言，以便预防并发症。阿昔洛韦是治疗的首选药物，但在等待诸如聚合酶链反应（PCR）和血清学等检测结果时，其使用往往会延迟。尽管细胞学检查结果快速且可靠，但在皮肤科，用于诊断目的的细胞学检查很少使用。我们报告一例通过细胞学检查诊断为由2型单纯疱疹病毒引起的新生儿疱疹病例。