低脂餐后服用缓释茶碱（Theolair-SR）的药代动力学特性与给药时间的关系。
Pharmacokinetic properties of sustained-release theophylline (Theolair-SR) in relation to timing of doses after low-fat meals.
作者信息
Welsh P W, O'Connell E J, Sachs M I, Moyer T P, Wick K A, Harrison L I, McCarville S E, Kvam D C
机构信息
Division of Allergic Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota.
出版信息
Ann Allergy. 1989 May;62(5):396-400.
PMID:2719348
Abstract
Pharmacodynamic and pharmacokinetic properties of sustained-release anyhdrous theophylline (Theolair-SR) were similar when doses were given either immediately after or two hours after low-fat meals in children with moderate asthma requiring daily theophylline maintenance. Asthma and pulmonary function values were maintained and approached values for healthy subjects during both treatment regimens.
摘要
对于需要每日服用茶碱维持治疗的中度哮喘儿童，当在低脂餐后立即或两小时后给予无水茶碱缓释剂（Theolair-SR）时，其药效学和药代动力学特性相似。在两种治疗方案中，哮喘和肺功能值均得以维持，并接近健康受试者的值。
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