Domson J F, Hein E W, Sheen A, Sly R M
Ann Allergy. 1979 Oct;43(4):220-2.
The effects of administration of single doses of 10 mg/kg of two sustained release theophylline preparations were compared in a double-blind, crossover study in eight asthmatic children. Serum theophylline concentrations were maintained well for 8-10 hours after administration of Theolair SR and 10 and 12 hours after administration of single doses of Theo-Dur.
在一项针对八名哮喘儿童的双盲交叉研究中,比较了单剂量10毫克/千克的两种缓释茶碱制剂的效果。服用Theolair SR后,血清茶碱浓度在8至10小时内保持良好;服用单剂量Theo-Dur后,血清茶碱浓度在10至12小时内保持良好。