Shields C L, Eagle R C
Department of Pathology, Wills Eye Hospital, Philadelphia, PA 19107.
Arch Ophthalmol. 1989 May;107(5):714-7. doi: 10.1001/archopht.1989.01070010732036.
A 29-year-old man sustained severe trauma to his left eye requiring corneoscleral wound repair and retinal detachment repair. Because of a persistent retinal detachment, he underwent vitrectomy and silicone oil implantation into the vitreous cavity. Over the ensuing 2 years 4 months, the eye gradually became glaucomatous, blind, and painful, requiring enucleation. Histopathologic examination revealed that coalescent globules of silicone oil had infiltrated the entire length of the attached atrophic optic nerve. Superficially reminiscent of the changes seen in Schnabel's cavernous optic atrophy, this observation provides evidence for the theory of Zimmerman et al concerning the pathogenesis of cavernous degeneration of the optic nerve in glaucomatous eyes.
一名29岁男性左眼遭受严重创伤，需要进行角巩膜伤口修复和视网膜脱离修复。由于视网膜持续脱离，他接受了玻璃体切除术并向玻璃体腔植入硅油。在随后的2年4个月里，该眼逐渐发展为青光眼、失明且疼痛，最终需要摘除眼球。组织病理学检查显示，聚结的硅油球浸润了附着的萎缩性视神经全长。这一观察结果表面上类似于施纳贝尔海绵状视神经萎缩所见的变化，为齐默尔曼等人关于青光眼性眼球视神经海绵状变性发病机制的理论提供了证据。
