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英国乳糜泻患者的长期护理:文献综述与未来方向

Long-term care for patients with coeliac disease in the UK: a review of the literature and future directions.

作者信息

Kurien M, Trott N, Sanders D S

机构信息

Department of Gastroenterology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.

Academic Unit of Gastroenterology, Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield, Sheffield, UK.

出版信息

J Hum Nutr Diet. 2016 Oct;29(5):617-23. doi: 10.1111/jhn.12379. Epub 2016 May 16.

DOI:10.1111/jhn.12379
PMID:27196331
Abstract

Coeliac disease is a common digestive disorder that affects 1% of adults. It is characterised by mucosal damage of the small intestine caused by dietary gluten. The main treatment for coeliac disease is a lifelong gluten-free diet, which can reduce morbidity and mortality and also improve quality of life. Despite the benefits, adhering to this diet is often challenging, with patients often struggling to sustain dietary restriction. Structured follow-up for coeliac disease is recommended in international guidelines for improving adherence and for detecting complications;however, uncertainty exists concerning exactly who should be administering this follow-up care. Here, we undertake a review of the current approaches described in the literature to follow-up patients with coeliac disease, and assess the efficacy of these differing models. We also explore future directions for the care of these patients in the context of the UK National Health Service (a publicly funded healthcare system). Although the focus of this review pertains to follow-up within the UK healthcare system, these problems are recognised to be international, and so the findings of our review are likely to be of interest to all healthcare professionals seeing and managing patients with coeliac disease.

摘要

乳糜泻是一种常见的消化系统疾病,影响着1%的成年人。其特征是由膳食麸质引起的小肠黏膜损伤。乳糜泻的主要治疗方法是终身无麸质饮食,这可以降低发病率和死亡率,还能提高生活质量。尽管有这些益处,但坚持这种饮食往往具有挑战性,患者常常难以维持饮食限制。国际指南建议对乳糜泻患者进行结构化随访,以提高依从性并检测并发症;然而,对于究竟应由谁来提供这种随访护理存在不确定性。在此,我们对文献中描述的当前随访乳糜泻患者的方法进行综述,并评估这些不同模式的疗效。我们还在英国国家医疗服务体系(一个由公共资金资助的医疗保健系统)的背景下探讨这些患者未来的护理方向。尽管本综述的重点是英国医疗保健系统内的随访,但这些问题被认为是国际性的,因此我们综述的结果可能会引起所有诊治乳糜泻患者的医疗专业人员的兴趣。

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