Departamento de Química, Universidade Estadual de Maringá, Avenida Colombo 5790, CEP: 87020-900 Maringá, Paraná, Brazil; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 610 Taylor Road, Piscataway, NJ 08854, United States.
Departamento de Química, Universidade Estadual de Maringá, Avenida Colombo 5790, CEP: 87020-900 Maringá, Paraná, Brazil.
Int J Biol Macromol. 2016 Oct;91:329-37. doi: 10.1016/j.ijbiomac.2016.05.056. Epub 2016 May 16.
The in situ synthesis of silver nanoparticles (AgNPs) within covalently-modified poly(ethylene terephthalate) (PET) films possessing ultra-thin layer of poly(vinyl alcohol) (PVA) and poly(acrylic acid) (PAA) is successfully demonstrated. The resulting polymeric films are shown to exhibit antimicrobial activities toward Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria and fungus (Candida albicans). To make the films, first PET surfaces were subject to photo-oxidation and subsequent solid-state grafting to attach a PVA layer, followed by a PAA layer. To synthesize the AgNPs inside the films, the PVA and PAA-modified PET was soaked in AgNO3 solution and the polymeric film was modified with the Ag(+) ions via Ag(+)-carboxylate interaction, and then the Ag(+) ions-containing polymer film was subject to either photo-reduction or thermal reduction processes. The PVA and PAA thin layers attached by covalent bonds to the PET surface uniquely promoted not only the in situ synthesis but also the stabilization of AgNPs. The formation of the AgNPs was confirmed by UV-vis spectroscopy or by monitoring the surface plasmon resonance (SPR) peak associated with AgNPs. The resulting PVA and PAA ultrathin layers modified and AgNPs containing PET served as bactericide and fungicide, inhibiting the growth of bacteria and fungi on the surfaces. Given PET's versatility and common use in many commercial processes, the method can be used for producing plastic surfaces with versatile antimicrobial and antibacterial properties.
成功地在具有超薄膜层的聚乙烯醇 (PVA) 和聚丙烯酸 (PAA) 的共价修饰的聚对苯二甲酸乙二醇酯 (PET) 薄膜内原位合成了银纳米粒子 (AgNPs)。结果表明，所得聚合物薄膜对革兰氏阳性（金黄色葡萄球菌）和革兰氏阴性（大肠杆菌）细菌和真菌（白色念珠菌）具有抗菌活性。为了制备这些薄膜，首先对 PET 表面进行光氧化，然后进行固态接枝以附着 PVA 层，然后附着 PAA 层。为了在薄膜内合成 AgNPs，将 PVA 和 PAA 修饰的 PET 浸泡在 AgNO3 溶液中，通过 Ag(+) - 羧酸相互作用使聚合物膜改性为 Ag(+) 离子，然后使含有 Ag(+) 离子的聚合物膜进行光还原或热还原过程。通过共价键附着在 PET 表面的 PVA 和 PAA 薄层不仅独特地促进了原位合成，而且还促进了 AgNPs 的稳定。AgNPs 的形成通过紫外-可见光谱或监测与 AgNPs 相关的表面等离子体共振 (SPR) 峰来确认。所得的 PVA 和 PAA 超薄层修饰和含 AgNPs 的 PET 用作杀菌剂和杀真菌剂，抑制细菌和真菌在表面的生长。鉴于 PET 的多功能性和在许多商业过程中的常见用途，该方法可用于生产具有多功能抗菌和抗菌性能的塑料表面。
