Li Tao, Zhou Xiaodong, Chen Zhi, Zhou Xingtao
Department of Ophthalmology (T.L., X.D.Z.), Jinshan Hospital of Fudan University, Shanghai, China; and Department of Ophthalmology (Z.C., X.T.Z.), Eye and ENT Hospital of Fudan University, Shanghai, China.
Eye Contact Lens. 2017 Sep;43(5):297-301. doi: 10.1097/ICL.0000000000000279.
To compare changes in the corneal thickness profile before and 6 months after femtosecond laser in situ keratomileusis (LASIK) for hyperopia.
In a prospective noncomparative case series study, 24 eyes of 20 hyperopic patients undergoing femtosecond LASIK were examined preoperatively and 6 months postoperatively. Corneal profile was measured using Pentacam HR device. Paired t test was used to compare preoperative and postoperative values. Spearman correlation analysis was performed to evaluate the relationship between the central corneal thickness changes and attempted spherical equivalent refraction (SER).
The mean uncorrected distance visual acuity significantly improved after surgery (P<0.001). Significant differences in central, midperipheral, ablative annular, and peripheral corneal thicknesses were observed from preoperatively to 6 months postoperatively (all P<0.001). There was no significant correlation between the changes in the central corneal thickness and attempted SER (P=0.23).
The corneal thicknesses across the whole ablation zone including central corneal thickness, significantly decrease postoperatively compared with preoperatively.
比较远视患者飞秒激光原位角膜磨镶术（LASIK）术前及术后6个月角膜厚度轮廓的变化。
在一项前瞻性非对照病例系列研究中，对20例接受飞秒LASIK的远视患者的24只眼进行术前和术后6个月检查。使用Pentacam HR设备测量角膜轮廓。采用配对t检验比较术前和术后的值。进行Spearman相关性分析以评估中央角膜厚度变化与预期等效球镜度（SER）之间的关系。
术后平均未矫正远视力显著提高（P<0.001）。术前至术后6个月，中央、中周边、消融环和周边角膜厚度均有显著差异（均P<0.001）。中央角膜厚度变化与预期SER之间无显著相关性（P=0.23）。
与术前相比，包括中央角膜厚度在内的整个消融区的角膜厚度在术后显著降低。
