移民人群中结核病治疗不依从风险因素的系统评价
Systematic review of risk factors for nonadherence to TB treatment in immigrant populations.
作者信息
Lin Stephanie, Melendez-Torres G J
机构信息
University of Oxford, Department of Social Policy and Intervention, Oxford, UK
University of Oxford, Department of Social Policy and Intervention, Oxford, UK.
出版信息
Trans R Soc Trop Med Hyg. 2016 May;110(5):268-80. doi: 10.1093/trstmh/trw025.
BACKGROUND
Foreign-born populations carry a significant TB burden in low-prevalence countries, composing over half of all cases in parts of Europe and North America. This study systematically reviewed evidence of risk factors for nonadherence to TB drug therapy in this group.
METHODS
On 28 October 2013 MEDLINE, CINAHL, Embase, PsychINFO and ProQuest were systematically searched for studies examining adherence in foreign-born populations with TB. Grey literature and reference lists were hand-searched. Risk factor studies were selected for inclusion if they consisted of at least 95% foreign-born populations.
RESULTS
Of 1761 studies identified in the search, 20 were included in the risk factor review. Undocumented immigration status, older age, and social risk factors were consistently correlated with nonadherence; gender, ethnicity, immigration time, education level, adverse side effects, and HIV status were inconsistently correlated; and behavioural risk factors and marital status were consistently not correlated.
CONCLUSIONS
This review emphasizes documentation status as a risk factor candidate for further investigation.
背景
在结核病低流行国家，外国出生人口承担着重大的结核病负担，在欧洲和北美的部分地区，这一群体的病例占所有病例的一半以上。本研究系统回顾了该群体中结核病药物治疗不依从风险因素的证据。
方法
2013年10月28日，对MEDLINE、CINAHL、Embase、PsychINFO和ProQuest进行了系统检索，以查找有关外国出生结核病患者治疗依从性的研究。同时手动检索灰色文献和参考文献列表。如果风险因素研究中至少95%为外国出生人口，则将其纳入。
结果
在检索到的1761项研究中，有20项被纳入风险因素综述。无证移民身份、年龄较大和社会风险因素与不依从始终相关；性别、种族、移民时间、教育水平、副作用和艾滋病毒感染状况与不依从的相关性不一致；行为风险因素和婚姻状况与不依从始终不相关。
结论
本综述强调将文件记录状况作为一个有待进一步调查的风险因素。
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