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一种用于癫痫手术评估的颅内脑电图（iEEG）脑功能映射工具。

An Intracranial Electroencephalography (iEEG) Brain Function Mapping Tool with an Application to Epilepsy Surgery Evaluation.

作者信息

Wang Yinghua, Yan Jiaqing, Wen Jianbin, Yu Tao, Li Xiaoli

机构信息

State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal UniversityBeijing, China; Center for Collaboration and Innovation in Brain and Learning Sciences, Beijing Normal UniversityBeijing, China.

School of Electrical and Control Engineering, North China University of Technology Beijing, China.

出版信息

Front Neuroinform. 2016 Apr 25;10:15. doi: 10.3389/fninf.2016.00015. eCollection 2016.

DOI:10.3389/fninf.2016.00015
PMID:27199729
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4842770/
Abstract

OBJECTS

Before epilepsy surgeries, intracranial electroencephalography (iEEG) is often employed in function mapping and epileptogenic foci localization. Although the implanted electrodes provide crucial information for epileptogenic zone resection, a convenient clinical tool for electrode position registration and Brain Function Mapping (BFM) visualization is still lacking. In this study, we developed a BFM Tool, which facilitates electrode position registration and BFM visualization, with an application to epilepsy surgeries.

METHODS

The BFM Tool mainly utilizes electrode location registration and function mapping based on pre-defined brain models from other software. In addition, the electrode node and mapping properties, such as the node size/color, edge color/thickness, mapping method, can be adjusted easily using the setting panel. Moreover, users may manually import/export location and connectivity data to generate figures for further application. The role of this software is demonstrated by a clinical study of language area localization.

RESULTS

The BFM Tool helps clinical doctors and researchers visualize implanted electrodes and brain functions in an easy, quick and flexible manner.

CONCLUSIONS

Our tool provides convenient electrode registration, easy brain function visualization, and has good performance. It is clinical-oriented and is easy to deploy and use. The BFM tool is suitable for epilepsy and other clinical iEEG applications.

摘要

目的

在癫痫手术前，颅内脑电图（iEEG）常用于功能映射和癫痫病灶定位。尽管植入电极可为癫痫病灶切除提供关键信息，但仍缺乏一种方便的临床工具用于电极位置配准和脑功能映射（BFM）可视化。在本研究中，我们开发了一种BFM工具，它有助于电极位置配准和BFM可视化，并应用于癫痫手术。

方法

BFM工具主要利用基于其他软件预定义脑模型的电极位置配准和功能映射。此外，使用设置面板可轻松调整电极节点和映射属性，如节点大小/颜色、边缘颜色/厚度、映射方法等。而且，用户可以手动导入/导出位置和连接性数据以生成图表供进一步应用。通过语言区定位的临床研究展示了该软件的作用。

结果

BFM工具帮助临床医生和研究人员以简单、快速且灵活的方式可视化植入电极和脑功能。

结论

我们的工具提供了方便的电极配准、易于实现的脑功能可视化，并且性能良好。它以临床为导向，易于部署和使用。BFM工具适用于癫痫及其他临床iEEG应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/b3c8b1071287/fninf-10-00015-g0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/5ac46de5d0b4/fninf-10-00015-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/0fdb56b41fcc/fninf-10-00015-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/96ab3a674bfd/fninf-10-00015-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/7960f1c6776d/fninf-10-00015-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/f8fea1c255b5/fninf-10-00015-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/8cc66c7ff63c/fninf-10-00015-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/2213d02bb695/fninf-10-00015-g0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/4de0361b36f5/fninf-10-00015-g0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/611dfd480aa4/fninf-10-00015-g0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/b3c8b1071287/fninf-10-00015-g0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/5ac46de5d0b4/fninf-10-00015-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/0fdb56b41fcc/fninf-10-00015-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/96ab3a674bfd/fninf-10-00015-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/7960f1c6776d/fninf-10-00015-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/f8fea1c255b5/fninf-10-00015-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/8cc66c7ff63c/fninf-10-00015-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/2213d02bb695/fninf-10-00015-g0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/4de0361b36f5/fninf-10-00015-g0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/611dfd480aa4/fninf-10-00015-g0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a8b/4842770/b3c8b1071287/fninf-10-00015-g0010.jpg

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