早产儿和足月儿胎粪中的微量元素。

Trace elements in meconium from preterm and full-term infants.

作者信息

Friel J K, Matthew J D, Andrews W L, Skinner C T

机构信息

Department of Biochemistry, Memorial University of Newfoundland, St. John's, Canada.

出版信息

Biol Neonate. 1989;55(4-5):214-7. doi: 10.1159/000242919.

DOI:10.1159/000242919

PMID:2719992

Abstract

Meconium samples from 23 preterm infants (birth weight = 1,097 +/- 359 g; gestational age 29 +/- 3 weeks, mean +/- SD) and 27 full-term infants (3,453 +/- 476 g; 39.5 +/- 1 weeks) were analyzed for zinc, copper, manganese, chromium and iron by atomic absorption spectrometry. Compared to meconium from preterm infants, full-term infants had an elevated (p less than 0.05) total excretion (microgram) of zinc (957 +/- 545 vs. 503 +/- 506), copper (245 +/- 256 vs. 128 +/- 94) and manganese (62 +/- 55 vs. 29 +/- 29), but not iron (190 +/- 147 vs. 332 +/- 532) or chromium (0.4 +/- 0.19 vs. 0.75 +/- 1.0). Two preterm infants had high losses (1.5 and 2 mg) of iron in their meconium. Zinc, copper and manganese losses into meconium appear to increase with gestation, whereas iron and chromium losses occur early in gestation and may be reabsorbed by term.

摘要

采用原子吸收光谱法对23例早产儿（出生体重=1097±359g；胎龄29±3周，均值±标准差）和27例足月儿（3453±476g；39.5±1周）的胎粪样本进行锌、铜、锰、铬和铁含量分析。与早产儿的胎粪相比，足月儿锌（957±545对503±506）、铜（245±256对128±94）和锰（62±55对29±29）的总排泄量（微克）升高（p<0.05），但铁（190±147对332±532）和铬（0.4±0.19对0.75±1.0）没有升高。两名早产儿的胎粪中铁损失量较高（分别为1.5mg和2mg）。胎粪中锌、铜和锰的损失似乎随着孕周增加而增加，而铁和铬的损失在妊娠早期发生，足月时可能会被重新吸收。