Murphy Susan L, Schepens Niemiec Stacey, Lyden Angela K, Kratz Anna L
Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI; VA Ann Arbor Health Care System (Geriatric Research, Education, and Clinical Center), Ann Arbor, MI.
Mrs. T.H. Chan Division of Occupational Science and Occupational Therapy, University of Southern California, Los Angeles, CA.
Arch Phys Med Rehabil. 2016 Sep;97(9 Suppl):S201-9. doi: 10.1016/j.apmr.2015.05.025. Epub 2016 May 17.
To examine how self-reported pain- and fatigue-related activity interference relates to symptoms and physical activity (PA) in daily life among people with knee or hip osteoarthritis.
Cross-sectional study with a 7-day repeated-measures assessment period.
General community.
Participants (N=154; mean age, 65y; 60% women [n=92]) with knee or hip osteoarthritis and pain lasting ≥3 months.
Not applicable.
Pain- or fatigue-related activity interference items on the Brief Pain Inventory or Brief Fatigue Inventory, respectively, from baseline survey, momentary pain and fatigue severity (measured 5times/d for 7d), and PA measured with a wrist-worn accelerometer over 7 days. We hypothesized that perception of pain- and fatigue-related activity interference would moderate the association between symptoms (pain or fatigue) and PA. People with higher pain- or fatigue-related activity interference were thought to have stronger negative associations between momentary ratings of pain and fatigue and PA than did those with lower activity interference.
Pain-related activity interference moderated the association between momentary pain and PA, but only in the first part of the day. Contrary to expectation, during early to midday (from wake-up time through 3 pm), low pain-related interference was associated with stronger positive associations between pain and PA but high pain-related interference was associated with a small negative association between pain and PA. Fatigue-related activity interference did not moderate the relation between fatigue and activity over the course of a day.
Depending on a person's reported level of pain-related activity interference, associations between pain and PA were different earlier in the day. Only those with high pain-related activity interference had lower levels of PA as pain increased and only in the morning. High pain-related activity interference may be important to address, particularly to maintain PA early in the day despite pain.
探讨自我报告的疼痛和疲劳相关活动干扰与膝关节或髋关节骨关节炎患者日常生活中的症状及身体活动（PA）之间的关系。
采用为期7天重复测量评估期的横断面研究。
普通社区。
154名膝关节或髋关节骨关节炎患者（平均年龄65岁；60%为女性[n = 92]），疼痛持续≥3个月。
不适用。
分别来自基线调查的简明疼痛量表或简明疲劳量表中与疼痛或疲劳相关的活动干扰项目、瞬时疼痛和疲劳严重程度（7天内每天测量5次）以及7天内使用腕部佩戴式加速度计测量的PA。我们假设，对疼痛和疲劳相关活动干扰的感知会调节症状（疼痛或疲劳）与PA之间的关联。与活动干扰较低的人相比，疼痛或疲劳相关活动干扰较高的人在疼痛和疲劳的瞬时评分与PA之间的负相关更强。
疼痛相关活动干扰调节了瞬时疼痛与PA之间的关联，但仅在一天的上午时段。与预期相反，在上午至中午（从起床时间到下午3点），低疼痛相关干扰与疼痛和PA之间更强的正相关相关，但高疼痛相关干扰与疼痛和PA之间较小的负相关相关。疲劳相关活动干扰在一天中并未调节疲劳与活动之间的关系。
根据个人报告的疼痛相关活动干扰水平，一天中较早时段疼痛与PA之间的关联有所不同。只有那些疼痛相关活动干扰较高的人在疼痛增加时PA水平较低，且仅在上午时段如此。解决高疼痛相关活动干扰可能很重要，特别是为了在一天中较早时段尽管疼痛仍能维持PA。
