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非系统性类固醇(吸入、鼻内和皮肤用)的不良反应:文献综述及建议的监测工具。

Adverse Effects of Nonsystemic Steroids (Inhaled, Intranasal, and Cutaneous): a Review of the Literature and Suggested Monitoring Tool.

机构信息

Winthrop University Hospital, 120 Mineola Blvd Suite 410, Mineola, NY, 11501, USA.

State University of New York, Stony Brook, NY, USA.

出版信息

Curr Allergy Asthma Rep. 2016 Jun;16(6):44. doi: 10.1007/s11882-016-0620-y.

DOI:10.1007/s11882-016-0620-y
PMID:27207481
Abstract

Inhaled, intranasal, and cutaneous steroids are prescribed by physicians for a plethora of disease processes including asthma and rhinitis. While the high efficacy of this class of medication is well known, the wide range of adverse effects, both local and systemic, is not well elucidated. It is imperative to monitor total steroid burden in its varied forms as well as tracking for possible side effects that may be caused by a high cumulative dose of steroids. This review article highlights the adverse effects of different steroid modalities as well as suggests a monitoring tool to determine steroid totality and side effects.

摘要

吸入剂、鼻内制剂和皮肤用皮质类固醇被医生用于治疗多种疾病,包括哮喘和鼻炎。尽管这类药物的高效性是众所周知的,但它们广泛的不良反应,包括局部和全身不良反应,尚未得到很好的阐明。监测各种形式的总类固醇负担以及跟踪可能由高累积剂量类固醇引起的副作用是至关重要的。本文综述了不同类固醇剂型的不良反应,并提出了一种监测工具来确定类固醇的总量和副作用。

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Adverse Effects of Nonsystemic Steroids (Inhaled, Intranasal, and Cutaneous): a Review of the Literature and Suggested Monitoring Tool.非系统性类固醇(吸入、鼻内和皮肤用)的不良反应:文献综述及建议的监测工具。
Curr Allergy Asthma Rep. 2016 Jun;16(6):44. doi: 10.1007/s11882-016-0620-y.
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Pediatr Pulmonol. 2011 Nov;46(11):1055-61. doi: 10.1002/ppul.21474. Epub 2011 Apr 25.
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Am Rev Respir Dis. 1993 Oct;148(4 Pt 2):S1-26. doi: 10.1164/ajrccm/148.4_Pt_2.S1.
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本文引用的文献

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Adrenal suppression by inhaled corticosteroids in patients with asthma: A systematic review and quantitative analysis.吸入性糖皮质激素对哮喘患者肾上腺功能的抑制作用:一项系统评价与定量分析。
Allergy Asthma Proc. 2016 Jan-Feb;37(1):9-17. doi: 10.2500/aap.2016.37.3912.
2
Intranasal corticosteroids do not affect intraocular pressure or lens opacity: a systematic review of controlled trials.鼻腔皮质类固醇不会影响眼压或晶状体混浊:对照试验的系统评价。
Rhinology. 2015 Dec;53(4):290-302. doi: 10.4193/Rhino15.020.
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Contact dermatitis: a practice parameter-update 2015.
Cells. 2024 Apr 30;13(9):767. doi: 10.3390/cells13090767.
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New Perspectives in the Management of Chronic Hand Eczema: Lessons from Pathogenesis.慢性手部湿疹管理的新视角:发病机制的启示。
Int J Mol Sci. 2023 Dec 27;25(1):362. doi: 10.3390/ijms25010362.
5
IL12/23 Blockade with Ustekinumab as a Treatment for Immune-Related Cutaneous Adverse Events.使用乌司奴单抗阻断IL12/23作为免疫相关皮肤不良事件的一种治疗方法。
Pharmaceuticals (Basel). 2023 Nov 2;16(11):1548. doi: 10.3390/ph16111548.
6
Nasal immune gene expression in response to azelastine and fluticasone propionate combination or monotherapy.鼻内免疫基因表达对氮卓斯汀和丙酸氟替卡松联合或单药治疗的反应。
Immun Inflamm Dis. 2022 Mar;10(3):e571. doi: 10.1002/iid3.571. Epub 2021 Nov 23.
7
Neuropsychiatric side reactions of leukotriene receptor antagonist, antihistamine, and inhaled corticosteroid: A real-world analysis of the Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS).白三烯受体拮抗剂、抗组胺药和吸入性糖皮质激素的神经精神方面不良反应:对美国食品药品监督管理局(FDA)不良事件报告系统(FAERS)的真实世界分析
World Allergy Organ J. 2021 Oct 1;14(10):100594. doi: 10.1016/j.waojou.2021.100594. eCollection 2021 Oct.
8
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Eur Arch Otorhinolaryngol. 2022 Jun;279(6):2915-2924. doi: 10.1007/s00405-021-07071-2. Epub 2021 Sep 24.
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Paediatric outpatient prescriptions in France between 2010 and 2019: A nationwide population-based study: Paediatric outpatient prescriptions in France, 2010 to 2019.2010年至2019年法国儿科门诊处方:一项基于全国人口的研究:2010年至2019年法国儿科门诊处方
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Local and systemic safety of intranasal corticosteroids.鼻内皮质类固醇的局部和全身安全性。
J Investig Allergol Clin Immunol. 2012;22(1):1-12.
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J Asthma. 2011 Oct;48(8):848-59. doi: 10.3109/02770903.2011.604883. Epub 2011 Aug 22.
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J Allergy Clin Immunol. 2011 Nov;128(5):956-63.e1-7. doi: 10.1016/j.jaci.2011.06.027. Epub 2011 Aug 4.