Roesler M, Wise L, Katayama K P
Advanced Institute of Fertility, Milwaukee, Wisconsin 53233.
Fertil Steril. 1989 Jun;51(6):1065-6. doi: 10.1016/s0015-0282(16)60748-3.
Pregnancies achieved by IVF and resulting in blighted ovum were karyotyped. The rate of aneuploidy was found to be 38% (5/13). In vitro fertilization does not appear to be a risk factor for chromosome anomaly in live births or miscarriages, and the data reported so far may suggest that aneuploid rates are actually lower for pregnancies achieved by IVF.
对通过体外受精(IVF)获得并导致空卵妊娠的胎儿进行了核型分析。发现非整倍体率为38%(5/13)。体外受精似乎不是活产或流产中染色体异常的危险因素,目前报道的数据可能表明,通过体外受精获得的妊娠中非整倍体率实际上更低。