Korth M, Horn F, Storck B, Jonas J
Augenklinik der Universität, Erlangen, Federal Republic of Germany.
Graefes Arch Clin Exp Ophthalmol. 1989;227(2):123-30. doi: 10.1007/BF02169783.
Pattern-onset electroretinograms (PERGs) were studied in 147 normal subjects of different ages (14-79 years) and in 110 eyes of 65 patients with glaucoma or ocular hypertension. The responses showed an increase (P less than 0.001) in peak latency with increasing age and a decrease (P less than 0.001) in amplitude which approximately parallels the loss of ganglion cells estimated by other authors. Many glaucoma eyes showed a loss of the normally present spatial tuning. In the age group above 50 years 50% of the onset responses were significantly diminished and the peak latencies were not significantly different. A negative correlation (P less than 0.001) was found between the size of the PERG and the cup/disc ratio and a positive correlation (P less than 0.001) with the area of the neuroretinal rim of the optic disc. The PERG decreased (P less than 0.01) with increasing visual field losses.
对147名不同年龄（14 - 79岁）的正常受试者以及65例青光眼或高眼压症患者的110只眼睛进行了图形起始视网膜电图（PERG）研究。结果显示，随着年龄增长，峰值潜伏期增加（P < 0.001），振幅降低（P < 0.001），这与其他作者估计的神经节细胞损失大致平行。许多青光眼患者的眼睛显示出正常存在的空间调谐丧失。在50岁以上年龄组中，50%的起始反应明显减弱，且峰值潜伏期无显著差异。PERG的大小与杯盘比呈负相关（P < 0.001），与视盘神经视网膜边缘面积呈正相关（P < 0.001）。随着视野缺损增加，PERG降低（P < 0.01）。
