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棘阿米巴角膜炎病例报告

Acanthamoeba keratitis challenges a case report.

作者信息

Cristina Stan, Cristina Vlăduţiu, Mihaela Popovici

出版信息

Rom J Ophthalmol. 2016 Jan-Mar;60(1):40-2.

PMID:27220232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5712919/
Abstract

Acanthamoeba keratitis is a rare, chronic, mainly contact lens-related infection caused by a free-living amoeba found ubiquitously in water and soil. A case of a 9-year-old child, who presented to our clinic with painful, red left eye, associated with photophobia, and decreased visual acuity, wais reported. The clinical examination revealed a discoid opacity inferiorly bounded by a dense, gray infiltrate. The progressive nature of the corneal infiltrate, the epithelial defect, and the lack of response to treatment was highly suggestive for Acanthamoeba keratitis. The distinctiveness of this case was the presence of Acanthamoeba keratitis in a child without a history of trauma or contact lens usage, the lack of an appropriate diagnosis and management of this vision-threatening infection.

摘要

棘阿米巴角膜炎是一种罕见的慢性感染,主要与隐形眼镜相关,由一种在水和土壤中普遍存在的自由生活阿米巴引起。本文报告了一例9岁儿童病例,该患儿因左眼疼痛、发红就诊于我院,伴有畏光和视力下降。临床检查发现下方有盘状混浊,边界为致密的灰色浸润。角膜浸润的进展性、上皮缺损以及对治疗无反应高度提示棘阿米巴角膜炎。该病例的独特之处在于患儿没有外伤或使用隐形眼镜的病史却发生了棘阿米巴角膜炎,且对这种威胁视力的感染缺乏恰当的诊断和处理。

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Acanthamoeba keratitis challenges a case report.棘阿米巴角膜炎病例报告
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Optom Vis Sci. 2013 Feb;90(2):e53-5. doi: 10.1097/OPX.0b013e31827f15b4.
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Acanthamoeba keratitis in a 5-year-old boy without a history of contact lens usage.一名5岁男孩患棘阿米巴角膜炎,无隐形眼镜使用史。
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引用本文的文献

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Successful culture of Acanthamoeba remains a key towards diagnosis of unusual clinical presentation of keratitis: A first case report from chhattisgarh.棘阿米巴的成功培养仍然是诊断不寻常临床表现角膜炎的关键:来自恰蒂斯加尔邦的首例病例报告。
J Family Med Prim Care. 2021 Oct;10(10):3904-3907. doi: 10.4103/jfmpc.jfmpc_369_21. Epub 2021 Nov 5.
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Evaluation of in vitro activity of five antimicrobial agents on Acanthamoeba isolates and their toxicity on human corneal epithelium.评价五种抗菌药物对棘阿米巴分离株的体外活性及其对人眼角膜上皮细胞的毒性。
Eye (Lond). 2022 Oct;36(10):1911-1917. doi: 10.1038/s41433-021-01768-8. Epub 2021 Sep 21.

本文引用的文献

1
Acanthamoeba keratitis in a 5-year-old boy without a history of contact lens usage.一名5岁男孩患棘阿米巴角膜炎,无隐形眼镜使用史。
Cornea. 2006 Apr;25(3):356-8. doi: 10.1097/01.ico.0000178723.26940.74.
2
Unusual case of Acanthamoeba polyphaga and Pseudomonas aeruginosa keratitis in a contact lens wearer from Gauteng, South Africa.南非豪登省一名隐形眼镜佩戴者发生多食棘阿米巴和铜绿假单胞菌角膜炎的罕见病例。
J Clin Microbiol. 2000 Feb;38(2):826-9. doi: 10.1128/JCM.38.2.826-829.2000.