Yamazaki Tomoo, Iwaya Yugo, Iwaya Mai, Watanabe Takayuki, Seki Ayako, Ochi Yasuhide, Hara Etsuo, Sekiguchi Tomohiro, Hosaka Noriko, Arakura Norikazu, Tanaka Eiji, Hasebe Osamu
Department of Gastroenterology, Nagano Municipal Hospital, Nagano, Japan.
Division of Gastroenterology and Hepatology, Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
Clin J Gastroenterol. 2016 Aug;9(4):222-7. doi: 10.1007/s12328-016-0653-8. Epub 2016 May 25.
A 77-year-old male with a long history of alcohol consumption and smoking was admitted for hoarseness and dysphagia. Computed tomography revealed thickening of the middle intrathoracic esophageal wall and multiple mediastinal lymph node swellings. Esophagogastroduodenoscopic examination disclosed an advanced-stage squamous cell carcinoma lesion in the middle intrathoracic esophagus with synchronous early stage Barrett's adenocarcinoma. The patient underwent endoscopic submucosal dissection for the adenocarcinoma followed by chemoradiation therapy for the squamous cell carcinoma. In spite of their common risk factors, the simultaneous manifestation of esophageal squamous cell carcinoma and Barrett's adenocarcinoma is extremely rare and requires further study.
一名有长期饮酒和吸烟史的77岁男性因声音嘶哑和吞咽困难入院。计算机断层扫描显示胸段食管中段壁增厚以及多个纵隔淋巴结肿大。食管胃十二指肠镜检查发现胸段食管中段有晚期鳞状细胞癌病变，同时伴有早期巴雷特腺癌。该患者接受了针对腺癌的内镜下黏膜下剥离术，随后针对鳞状细胞癌进行了放化疗。尽管存在共同的危险因素，但食管鳞状细胞癌和巴雷特腺癌同时出现极为罕见，需要进一步研究。
