用于纳米显微镜的荧光探针：四类及多种可能性
Fluorescent probes for nanoscopy: four categories and multiple possibilities.
作者信息
Ni Ming, Zhuo Shuangmu, So Peter T C, Yu Hanry
机构信息
Fujian Provincial Key Laboratory for Photonics Technology & Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, 350007, China.
Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore, 138669, Singapore.
出版信息
J Biophotonics. 2017 Jan;10(1):11-23. doi: 10.1002/jbio.201600042. Epub 2016 May 25.
Abstract
Nanoscopy enables breaking down the light diffraction limit and reveals the nanostructures of objects being studied using light. In 2014, three scientists pioneered the development of nanoscopy and won the Nobel Prize in Chemistry. This recognized the achievement of the past twenty years in the field of nanoscopy. However, fluorescent probes used in the field of nanoscopy are still numbered. Here, we review the currently available four categories of probes and existing methods to improve the performance of probes.
摘要
纳米显微镜能够突破光衍射极限，并揭示使用光来研究的物体的纳米结构。2014年，三位科学家率先开发了纳米显微镜，并获得了诺贝尔化学奖。这认可了纳米显微镜领域过去二十年的成就。然而，纳米显微镜领域中使用的荧光探针数量仍然有限。在此，我们综述了目前可用的四类探针以及提高探针性能的现有方法。
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