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自组装超短肽在生物纳米技术中的应用

Applications of self-assembling ultrashort peptides in bionanotechnology.

作者信息

Ni Ming, Zhuo Shuangmu

机构信息

Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of Optoelectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University Fuzhou 350007 P. R. China

School of Biological Sciences & Engineering, Yachay Tech University Hacienda San José s/n San Miguel de Urcuquí 100105 Ecuador.

出版信息

RSC Adv. 2019 Jan 8;9(2):844-852. doi: 10.1039/c8ra07533f. eCollection 2019 Jan 2.

Abstract

Peptides are intriguing building blocks for a variety of applications in bionanotechnology. Peptides can self-assemble into well-ordered nanostructures. Among the various nanomorphology forms, peptide nanofibers and nanotubes are relevant in biomedical applications. In this review, their applications as tissue engineering scaffolds, drug delivery vehicles, three-dimensional printing bioinks and bioimaging nanoprobes will be illustrated. This review article describes di-, tri-, tetra-peptides because they are cost-effective, simple to prepare, and amenable to production on a large scale.

摘要

肽是生物纳米技术中各种应用的有趣构建块。肽可以自组装成有序的纳米结构。在各种纳米形态形式中,肽纳米纤维和纳米管在生物医学应用中具有相关性。在本综述中,将说明它们作为组织工程支架、药物递送载体、三维打印生物墨水和生物成像纳米探针的应用。这篇综述文章描述了二肽、三肽、四肽,因为它们具有成本效益、制备简单且适合大规模生产。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ee1/9059570/2f28d18fe6be/c8ra07533f-f1.jpg

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