Department of Pathology, City of Hope National Medical Center, Duarte, California, USA.
J Gastrointest Oncol. 2012 Sep;3(3):262-84. doi: 10.3978/j.issn.2078-6891.2012.019.
Gastrointestinal tract tumors include a wide variety of vastly different tumors and on a whole are one of the most common malignancies in western countries. These tumors often present at late stages as distant metastases which are then biopsied and may be difficult to differentiate without the aid of immunohistochemical stains. With the exception of pancreatic and biliary tumors where there are no distinct immunohistochemical patterns, most gastrointestinal tumors can be differentiated by their unique immunohistochemical profile. As the size of biopsies decrease, the role of immunohistochemical stains will become even more important in determining the origin and differentiation of gastrointestinal tract tumors.
胃肠道肿瘤包括了广泛的差异极大的肿瘤，整体而言是西方国家最常见的恶性肿瘤之一。这些肿瘤通常在远处转移阶段才被发现，此时进行活检，若没有免疫组织化学染色的帮助，可能很难进行区分。除了胰腺和胆道肿瘤外，它们没有明显的免疫组织化学模式，大多数胃肠道肿瘤可以通过其独特的免疫组织化学特征来区分。随着活检标本体积的减小，免疫组织化学染色在确定胃肠道肿瘤的起源和分化方面的作用将变得更加重要。
