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腹腔镜与开腹子宫切除术治疗巨大子宫(≥1500克)女性良性疾病的可行性及结局

Laparoscopic Versus Open Hysterectomy for Benign Disease in Women with Giant Uteri (≥1500 g): Feasibility and Outcomes.

作者信息

Uccella Stefano, Casarin Jvan, Marconi Nicola, Cromi Antonella, Morosi Chiara, Gisone Baldo, Pinelli Ciro, Ghezzi Fabio

机构信息

Department of Obstetrics and Gynecology, University of Insubria, F. Del Ponte Hospital, Varese, Italy.

Department of Obstetrics and Gynecology, University of Insubria, F. Del Ponte Hospital, Varese, Italy.

出版信息

J Minim Invasive Gynecol. 2016 Sep-Oct;23(6):922-7. doi: 10.1016/j.jmig.2016.05.002. Epub 2016 May 17.

Abstract

UNLABELLED

STUDY

OBJECTIVE

To evaluate perioperative outcomes and complications of laparoscopic hysterectomy (LH) in women with giant uteri (≥1.5 kg) compared with open abdominal hysterectomy (AH), which is considered the reference.

DESIGN

A retrospective analysis of prospectively collected data (Canadian Task Force Classification II-2).

SETTING

An academic research center.

PATIENTS

All consecutive women who underwent hysterectomy for uteri weighing ≥1500 g (total = 51) between 2000 and 2015 were analyzed. Twenty-seven (53%) patients had been scheduled for the laparoscopic approach (LH), whereas 24 (48%) had been scheduled for AH.

INTERVENTIONS

Hysterectomy ± mono/bilateral salpingo-oophorectomy.

MAIN OUTCOME MEASURES

Perioperative details, incidence, severity, and type of complications were analyzed according to surgical approach (AH vs LH). We also evaluated the trends over time in terms of perioperative outcomes.

RESULTS

AH was associated with a shorter operative time (97.5 vs 160 minutes, p = .004) compared with LH. Blood loss (200 vs 225 mL, p = .21) and the decrease in postoperative hemoglobin (-1.2 vs -1.1, p = .89) were similar between AH and LH. Intra- and postoperative complications were similar between the 2 groups; however, hospital stay was significantly shorter in the LH group (median = 3 days vs 1 day, p < .001). A significant trend toward a progressive increase in the use of the minimally invasive approach was registered through the years (p = .001). Parallel to this increase, we observed a significant reduction in terms of length of stay. Moreover, a decrease in the total number of complications, mainly because of a decrease in the rate of early minor events, was observed through the years.

CONCLUSIONS

Our experience shows that LH can be considered a feasible procedure, even in cases of uteri ≥1.5 kg, with significant advantages over open surgery in terms of postoperative hospital stay.

摘要

未加标注

研究

目的

与被视为参照的开腹子宫切除术(AH)相比,评估巨大子宫(≥1.5千克)女性行腹腔镜子宫切除术(LH)的围手术期结局及并发症。

设计

对前瞻性收集的数据进行回顾性分析(加拿大工作组分类II-2)。

地点

一个学术研究中心。

患者

分析了2000年至2015年间所有连续接受子宫切除术且子宫重量≥1500克的女性(共51例)。27例(53%)患者计划采用腹腔镜手术(LH),而24例(48%)计划采用AH。

干预措施

子宫切除术±单侧/双侧输卵管卵巢切除术。

主要观察指标

根据手术方式(AH与LH)分析围手术期细节、并发症的发生率、严重程度及类型。我们还评估了围手术期结局随时间的变化趋势。

结果

与LH相比,AH的手术时间较短(97.5分钟对160分钟,p = 0.004)。AH和LH之间的失血量(200毫升对225毫升,p = 0.21)及术后血红蛋白下降幅度(-1.2对-1.1,p = 0.89)相似。两组的术中及术后并发症相似;然而,LH组的住院时间明显更短(中位数 = 3天对1天,p < 0.001)。多年来,微创方法的使用呈显著的逐渐增加趋势(p = 0.001)。与此增加趋势并行,我们观察到住院时间显著缩短。此外,多年来并发症总数有所减少,主要是因为早期轻微事件的发生率降低。

结论

我们的经验表明,即使对于子宫≥1.5千克的病例,LH也可被视为一种可行的手术,在术后住院时间方面比开放手术具有显著优势。

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