Guiso Nicole, Wirsing von König Carl Heinz
a Institut Pasteur, Molecular Prevention and Therapy of Human Infectious Diseases Unit , Paris , France.
b Labor:Medizin Krefeld MVZ , Krefeld , Germany.
Expert Rev Anti Infect Ther. 2016 Jul;14(7):657-67. doi: 10.1080/14787210.2016.1190272. Epub 2016 May 31.
Pertussis or whooping cough is a respiratory disease caused by Bordetella pertussis or, to a lesser extent, by B. parapertussis. Vaccines against pertussis have been widely used for more than 50 years and have led to a significant reduction of morbidity and mortality. However, even in countries with a high vaccine coverage, the disease is still not well controlled. Surveillance is urgently needed.
This review summarizes surveillance methods and gives examples that may be used when setting up a surveillance program or analyzing an outbreak. Expert commentary: Pertussis surveillance is urgently required in order to define the burden of disease, to adapt vaccine strategies according to the type of pertussis vaccine used and to follow the evolution of the bacteria.
百日咳是由百日咳博德特氏菌引起的一种呼吸道疾病,在较小程度上也可由副百日咳博德特氏菌引起。针对百日咳的疫苗已广泛使用五十多年,显著降低了发病率和死亡率。然而,即使在疫苗接种覆盖率高的国家,该疾病仍未得到有效控制。迫切需要进行监测。
本综述总结了监测方法,并给出了在建立监测项目或分析疫情时可能使用的示例。专家评论:迫切需要进行百日咳监测,以确定疾病负担,根据所用百日咳疫苗的类型调整疫苗策略,并跟踪细菌的演变情况。