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New antitumor antibiotic, FR-900462. II. Production, isolation, characterization and biological activity.

作者信息

Iwami M, Nakayama O, Okuhara M, Terano H, Kohsaka M

机构信息

Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Ibaraki, Japan.

出版信息

J Antibiot (Tokyo). 1989 May;42(5):686-90. doi: 10.7164/antibiotics.42.686.

DOI:10.7164/antibiotics.42.686
PMID:2722682
Abstract

FR-900462 is a new antitumor antibiotic produced by Streptomyces tokashikiensis No. 7124. It was highly active against leukemia P388 and melanoma B16. Furthermore, it has weak antimicrobial activity against some Gram-positive bacteria.

摘要

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