Derelanko M J, LoBue J, Gordon A S, Camiscoli J F, Gizzi C, Fredrickson T N
Exp Hematol. 1978 Jan;6(1):91-5.
Erythropoietin (Ep) levels were measured in Shay chloroleukemic rats at various stages of anemia. Serum Ep was shown to increase logarithmically as the anemia became more severe. This increase in Ep levels was similar to that observed in normal rats subjected to acute blood loss. Significant levels of Ep were also demonstrated in ascitic fluid extracted from the peritoneal cavity of leukemic rats. These results indicate that the anemia of this disease is not due to a diminished production of Ep.
在患贫血不同阶段的沙伊氏氯白血病大鼠中测定了促红细胞生成素（Ep）水平。结果显示，随着贫血加重，血清Ep呈对数增加。Ep水平的这种增加与急性失血的正常大鼠中观察到的情况相似。从白血病大鼠腹腔提取的腹水中也检测到了显著水平的Ep。这些结果表明，该疾病的贫血并非由于Ep生成减少所致。
