几起非专业使用甲基丙烯酸酯紫外线固化指甲油引起的不良反应案例。
Several cases of undesirable effects caused by methacrylate ultraviolet-curing nail polish for non-professional use.
作者信息
Dahlin Jakob, Berne Berit, Dunér Kari, Hosseiny Sara, Matura Mihály, Nyman Gunnar, Tammela Monica, Isaksson Marléne
机构信息
Department of Occupational and Environmental Dermatology, Skåne University Hospital, 205 02, Malmö, Sweden.
Department of Medical Sciences, Dermatology and Venereology, Uppsala University, 751 85, Uppsala, Sweden.
出版信息
Contact Dermatitis. 2016 Sep;75(3):151-6. doi: 10.1111/cod.12608. Epub 2016 May 27.
BACKGROUND
Ultraviolet (UV)-curing nail polishes based on acrylates or methacrylates are currently also available for non-professional use. The Swedish Medical Products Agency recently prohibited one brand of UV-curing polish, because several consumers reported undesirable effects after using it.
OBJECTIVES
To investigate whether consumers with undesirable effects after using the UV-curing nail polish that was later prohibited were contact allergic to the polish and its individual ingredients.
MATERIALS/METHODS: Eight patients who had reported severe skin reactions after the use of the UV-curing polish were patch tested with two coatings of the nail polish and its ingredients at five dermatology departments in Sweden.
RESULTS
All patients tested except one showed contact allergic reactions to one or several of the acrylate-based or methacrylate-based ingredients in the nail polish.
CONCLUSIONS
The non-professional use of UV-curing nail polishes poses a risk of sensitization from acrylates and methacrylates.
背景
基于丙烯酸酯或甲基丙烯酸酯的紫外线固化指甲油目前也可供非专业人士使用。瑞典医疗产品管理局最近禁止了一个品牌的紫外线固化指甲油，因为有几位消费者在使用后报告了不良影响。
目的
调查使用后来被禁止的紫外线固化指甲油后出现不良影响的消费者是否对该指甲油及其个别成分产生接触性过敏。
材料/方法：在瑞典的五个皮肤科部门，对八名报告在使用紫外线固化指甲油后出现严重皮肤反应的患者，用两层指甲油及其成分进行斑贴试验。
结果
除一名患者外，所有接受测试的患者均对指甲油中一种或几种基于丙烯酸酯或甲基丙烯酸酯的成分出现接触性过敏反应。
结论
非专业使用紫外线固化指甲油存在因丙烯酸酯和甲基丙烯酸酯导致致敏的风险。
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