白塞氏视网膜血管炎患者超广角荧光素血管造影评分的观察者间差异
Inter-observer Variability in Scoring Ultra-wide-field Fluorescein Angiography in Patients with Behçet Retinal Vasculitis.
作者信息
Moon Sang Woong, Kim Bo Hyuck, Park Un Chul, Yu Hyeong Gon
机构信息
a Department of Ophthalmology , Kyung Hee University College of Medicine , Seoul , Korea.
b Department of Ophthalmology , Seoul National University College of Medicine , Seoul , Korea.
出版信息
Ocul Immunol Inflamm. 2017 Feb;25(1):20-28. doi: 10.1080/09273948.2016.1175640. Epub 2016 May 26.
PURPOSE
To test inter-observer agreement in applying the scoring system of the Angiography Scoring of Uveitis Working Group (ASUWG) to ultra-wide-field fluorescein angiograms (UWFA) obtained from patients with Behçet retinal vasculitis.
METHODS
Both standard FA and UWFA images were obtained from 21 patients with retinal vasculitis associated with Behçet disease. Three graders independently graded 21 series of standard FA and 21 series of UWFA images. Spearman rank correlation and the intra-class correlation coefficient (ICC) were used to analyze the correlations.
RESULTS
Total scores of all angiographic signs observed in both UWFA and standard FA images were significantly correlated between each pair of graders and among the three graders (ICC of standard FA = 0.874, p<0.001; ICC of UWFA = 0.928, p<0.001).
CONCLUSIONS
The ASUWG scoring system is a reliable method of scoring UWFA images with regard to judging the activity of retinal vasculitis in ocular Behçet disease.
目的
测试在将葡萄膜炎血管造影评分工作组（ASUWG）的评分系统应用于从白塞氏视网膜血管炎患者获得的超广角荧光血管造影（UWFA）时观察者间的一致性。
方法
从21例患有与白塞氏病相关的视网膜血管炎患者获取标准荧光血管造影（FA）和UWFA图像。三名分级者独立对21组标准FA图像和21组UWFA图像进行分级。使用Spearman等级相关性和组内相关系数（ICC）分析相关性。
结果
在UWFA和标准FA图像中观察到的所有血管造影体征的总分在每对分级者之间以及三名分级者之间均显著相关（标准FA的ICC = 0.874，p<0.001；UWFA的ICC = 0.928，p<0.001）。
结论
就判断眼部白塞氏病视网膜血管炎的活动性而言，ASUWG评分系统是对UWFA图像进行评分的可靠方法。
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