Bazvand Fatemeh, Zarei Mohammad, Ebrahimiadib Nazanin, Karkhaneh Reza, Davoudi Samaneh, Soleimanzadeh Mahyar, Sharifian Elaheh, Roohipoor Ramak, Modjtahedi Bobeck S
a Eye Research Center, Farabi Eye Hospital , Tehran University of Medical Sciences , Tehran , Iran.
b Retina Service, Department of Ophthalmology , Massachusetts Eye and Ear Infirmary, Harvard Medical School , Boston , MA , USA.
Semin Ophthalmol. 2017;32(6):764-771. doi: 10.1080/08820538.2016.1178310. Epub 2016 Aug 10.
Evaluating the ocular manifestation and fundus fluorescein angiography (FA) findings of patients with Behçet's disease as well as the relationship between visual acuity and angiographic findings.
Retrospective chart review of patients with Behçet's disease seen at the Farabi Eye Hospital.
Forty-six patients (92 eyes) with mean age of 33.41 ± 10.67 were included. The most frequent presenting symptom and sign were reduced vision (76%) and uveitis (87%), respectively. Panuveitis was the most frequent type of uveitis (76%). Among patients with FA, vasculitis was the most common finding (87%) and it was significantly more severe among patients with visual acuity less than 20/200. Macular leakage (P = 0.001), arterial narrowing (P = 0.000), and posterior retinal vasculitis (P = 0.002) on FA were all associated with worsening final visual acuity.
The most common ocular findings in Behçet's disease were panuveitis and vasculitis. Location of vasculitis, arterial narrowing, and macular leakage on initial FA may predict visual prognosis.
评估白塞病患者的眼部表现、眼底荧光血管造影（FA）结果以及视力与血管造影结果之间的关系。
对法拉比眼科医院收治的白塞病患者进行回顾性病历审查。
纳入46例患者（92只眼），平均年龄为33.41±10.67岁。最常见的症状和体征分别是视力下降（76%）和葡萄膜炎（87%）。全葡萄膜炎是最常见的葡萄膜炎类型（76%）。在接受FA检查的患者中，血管炎是最常见的发现（87%），并且在视力低于20/200的患者中明显更严重。FA上的黄斑渗漏（P = 0.001）、动脉狭窄（P = 0.000）和视网膜后血管炎（P = 0.002）均与最终视力恶化相关。
白塞病最常见的眼部表现是全葡萄膜炎和血管炎。初始FA上血管炎的位置、动脉狭窄和黄斑渗漏可能预测视力预后。
