Davis Alexander, Navin Nicholas E
Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Genome Biol. 2016 May 26;17(1):113. doi: 10.1186/s13059-016-0987-z.
Computational methods have been developed to reconstruct evolutionary lineages from tumors using single-cell genomic data. The resulting tumor trees have important applications in cancer research and clinical oncology.Please see related Research articles: http://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-0929-9 and http://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-0936-x .
已经开发出计算方法，用于使用单细胞基因组数据从肿瘤中重建进化谱系。由此产生的肿瘤树在癌症研究和临床肿瘤学中具有重要应用。请参阅相关研究文章：http://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-0929-9和http://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-0936-x 。
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