Tambo Ernest, Chen Jun-Hu, Zhou Xiao-Nong, Khater Emad I M
Department of Biochemistry and Pharmaceutical Sciences, Higher Institute of Public Health Sciences, Université des Montagnes, Bangangté, Cameroon.
Africa Disease Intelligence and Surveillance, Communication and Response (Africa DISCoR) Foundation, Yaoundé, Cameroon.
Infect Dis Poverty. 2016 May 27;5(1):56. doi: 10.1186/s40249-016-0148-3.
Dengue is still a substantial vector-borne viral disease threat and burden of public health importance worldwide. This situation is complicated by dengue virus unprecedented resurgence and persistence of varied serotypes in endemic-prone areas, and man-made and natural activities consequences that promote vector emergence, transmission dynamics and spread across the Asia-Pacific region. There is an urgent need to strengthen operational and contextual surveillance-response research in improving early detection of active reservoir detection, novel drug in case management and quality evidence-based response including the deployment of dengue mass vaccination. Moreover, sustained mapping and watching of dengue risk factors or determinants, performance and outcome indicators of control or elimination programs effectiveness in defining minimum effective data towards community knowledge-based decision-making policy and effective response packages is imperative. Moreover, implementation of a robust, integrated dengue early warning surveillance, monitoring and response systems metrics is required for evidence-based, timely and cost-effective contextual mitigation strategies, and innovative interventions.
登革热仍然是一种严重的媒介传播病毒性疾病，在全球范围内构成对公共卫生具有重要意义的威胁和负担。登革热病毒在流行易发生地区前所未有的复苏以及多种血清型的持续存在，以及促进病媒出现、传播动态和在亚太地区传播的人为和自然活动后果，使这种情况变得复杂。迫切需要加强业务和背景监测-应对研究，以改进对活跃宿主的早期检测、病例管理中的新型药物以及包括登革热大规模疫苗接种部署在内的基于质量证据的应对措施。此外，持续绘制和监测登革热风险因素或决定因素、控制或消除计划有效性的绩效和结果指标，以确定基于社区知识的决策政策和有效应对方案所需的最低有效数据，这是必不可少的。此外，需要实施强大的综合登革热早期预警监测、监测和应对系统指标，以制定基于证据、及时且具有成本效益的背景缓解策略和创新干预措施。
