登革热：持续的全球威胁。
Dengue: a continuing global threat.
机构信息
Instituto de Medicina Tropical, 'Pedro Kouri', PO Box 601, Marianao 13, Ciucad de la Habana, Cuba.
出版信息
Nat Rev Microbiol. 2010 Dec;8(12 Suppl):S7-16. doi: 10.1038/nrmicro2460.
Abstract
Dengue fever and dengue haemorrhagic fever are important arthropod-borne viral diseases. Each year, there are ∼50 million dengue infections and ∼500,000 individuals are hospitalized with dengue haemorrhagic fever, mainly in Southeast Asia, the Pacific and the Americas. Illness is produced by any of the four dengue virus serotypes. A global strategy aimed at increasing the capacity for surveillance and outbreak response, changing behaviours and reducing the disease burden using integrated vector management in conjunction with early and accurate diagnosis has been advocated. Antiviral drugs and vaccines that are currently under development could also make an important contribution to dengue control in the future.
摘要
登革热和登革出血热是重要的虫媒病毒病。每年，约有 5000 万例登革热感染病例，约有 50 万人因登革出血热住院，主要集中在东南亚、太平洋和美洲。这四种登革热病毒血清型都可引起疾病。目前提倡采取一项全球战略，通过综合病媒管理，结合早期和准确的诊断，来提高监测和疫情应对能力、改变行为以及减轻疾病负担。目前正在开发的抗病毒药物和疫苗也将对未来的登革热控制做出重要贡献。
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