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[乳腺血管肉瘤]

[Angiosarcoma of the breast].

作者信息

Malavaud B, Pessonnier A, Martel P, Roche H, Marques B

机构信息

Centre Claudius Regaud, Toulouse.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1989;18(2):173-6.

PMID:2723347
Abstract

Angiosarcoma of the breast is a rare connective tissue tumour, there having been fewer than 100 cases described. It occurs practically only in women and presents as a phylloid tumour of rapid growth in a young woman. There may be inflammatory phenomena; local trauma is often mentioned. The diagnosis is difficult and relies on the histological examination of biopsy specimens or of the whole specimen removed. The microscopic appearance may be very similar to that of a benign haemangioma. It is necessary to make several cuts and to remember the essential feature of a haemangioma of the breast, namely that it is subclinical and therefore usually discovered microscopically by chance. Treatment consists of simple mastectomy without usually needing to clear the axilla. It is necessary to give polychemotherapy. There is still no agreement on radiotherapy and hormone therapy. The prognosis is very serious because the mean length of survival is around 22 months. We report a recent case of angiosarcoma of the breast in which diagnostic steps were taken in order, and for which expert histological opinion made it possible to diagnose the condition in less than one month. A 37 year old woman had been complaining of the recent appearance of a tumour in her right breast which was growing rapidly because at the first consultation, within one month after her first signs, it measured 50 mm in diameter. It was poorly outlined, multinodular and non-inflammatory.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

乳腺血管肉瘤是一种罕见的结缔组织肿瘤,报道的病例不足100例。它实际上仅发生于女性,表现为年轻女性中生长迅速的叶状肿瘤。可能存在炎症现象;常提及局部创伤。诊断困难,依赖于活检标本或切除的整个标本的组织学检查。显微镜下表现可能与良性血管瘤非常相似。需要做多个切片,并记住乳腺血管瘤的基本特征,即它是亚临床的,因此通常是偶然通过显微镜发现的。治疗包括单纯乳房切除术,通常无需清扫腋窝。需要进行多药化疗。对于放疗和激素治疗仍未达成共识。预后非常严重,因为平均生存时间约为22个月。我们报告了一例近期的乳腺血管肉瘤病例,该病例按顺序采取了诊断步骤,专家组织学意见使得在不到一个月的时间内确诊了该病。一名37岁女性一直抱怨其右乳近期出现肿瘤,且生长迅速,因为在首次就诊时,即出现最初症状后的一个月内,肿瘤直径达50毫米。它轮廓不清,呈多结节状,无炎症。(摘要截短于250字)

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