Arancia G, Crateri Trovalusci P, Mariutti G, Mondovì B
Laboratory of Ultrastructures, Istituto Superiore di Sanità, Rome, Italy.
Int J Hyperthermia. 1989 May-Jun;5(3):341-50. doi: 10.3109/02656738909140460.
The effects of hyperthermic treatment on some intracellular components and on the general morphology of Chinese hamster V79 fibroblasts have been studied. After 1 h of heating at 42 degrees C cells show small interruptions of the plasma membrane, dilation of the mitochondrial cristae and dissociation of the polyribosomes. These modifications become progressively more pronounced after 1 or 3 h treatment at 43 degrees C. Severe alterations in the general morphology of the cells are evident after 1 h heating at 45 degrees C.
