Jung S S, Weiman T J
J Ky Med Assoc. 1989 May;87(5):227-9.
Thirty-six malignant and four benign endotracheal and endobronchial lesions were treated using Nd:YAG laser through flexible bronchoscope from November 1985 to July 1987 at the University Hospital in Louisville, Kentucky. Progressive dyspnea and hemoptysis were primary indications for the procedures. The majority of patients were treated under general anesthesia using intravenous agents. Most patients required two treatment sessions for complete endobronchial tumor ablation. The mean hospital stay was 48 hours. Two patients died postoperatively; one died of myocardial infarction and another of progressive respiratory failure. The mean survival was 13 weeks. Sixty-three percent of patients treated were improved as measured by Karnofsky Performance Status. Mean change in Performance Status between pre- and post-laser treatment was 100% (from 30 to 60). We conclude that therapeutic laser bronchoscopy is a useful adjunctive treatment in selected patients with obstructing or bleeding lung tumors.
1985年11月至1987年7月期间，在肯塔基州路易斯维尔大学医院，通过可弯曲支气管镜使用钕钇铝石榴石激光对36例恶性和4例良性气管内及支气管内病变进行了治疗。进行性呼吸困难和咯血是这些操作的主要指征。大多数患者在全身麻醉下使用静脉药物进行治疗。大多数患者需要两个疗程的治疗才能完全消融支气管内肿瘤。平均住院时间为48小时。两名患者术后死亡；一名死于心肌梗死，另一名死于进行性呼吸衰竭。平均生存期为13周。根据卡氏功能状态评分，63%接受治疗的患者病情有所改善。激光治疗前后功能状态的平均变化为100%（从30提高到60）。我们得出结论，对于选定的患有阻塞性或出血性肺部肿瘤的患者，治疗性激光支气管镜检查是一种有用的辅助治疗方法。
