Kamata Satoshi, Sakurada Akira, Sato Nobuyuki, Noda Masafumi, Okada Yoshinori
Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan.
Department of Thoracic Surgery, Aomori Prefectural Central Hospital, Aomori, Japan.
Gen Thorac Cardiovasc Surg. 2017 Jun;65(6):361-364. doi: 10.1007/s11748-016-0666-8. Epub 2016 May 28.
Primary pulmonary choriocarcinoma is a very rare tumor and eventually diagnosed by pulmonary resection. A poor prognosis has been reported for this disease, but appropriate treatment has not been established. Here, we report the successful surgical treatment for a primary pulmonary choriocarcinoma. A 70-year-old male presented with cough and a 3.8-cm solid tumor was detected in the right upper lobe of the lung on CT scan. Results of an open lung biopsy indicated carcinoma with indeterminate histological subtype. Right upper lobectomy was performed and the permanent pathological diagnosis was choriocarcinoma. Right after surgery, systemic and genital screening was performed by urologist, but no abnormal findings were observed. Elevation of serum β-hCG was confirmed at the same time and the value dropped within normal range in 2 months. According to diagnosis criteria, we reached final diagnosis of primary pulmonary choriocarcinoma. The patient has been alive with no recurrence for 2 years after surgery.
原发性肺绒毛膜癌是一种非常罕见的肿瘤，最终通过肺切除术确诊。据报道，这种疾病预后较差，但尚未确立适当的治疗方法。在此，我们报告一例原发性肺绒毛膜癌的成功手术治疗病例。一名70岁男性因咳嗽就诊，CT扫描显示右肺上叶有一个3.8厘米的实性肿瘤。开胸肺活检结果显示为组织学亚型不确定的癌。进行了右上肺叶切除术，最终病理诊断为绒毛膜癌。术后立即由泌尿科医生进行了全身和生殖器检查，但未发现异常。同时血清β-hCG升高，2个月内降至正常范围。根据诊断标准，我们最终诊断为原发性肺绒毛膜癌。该患者术后已存活2年，无复发。
